2024年12月24日 · ART4 (ADP-Ribosyltransferase 4 (Inactive) (Dombrock Blood Group)) is a Protein Coding gene. Diseases associated with ART4 include Blood Group, Dombrock System and Sickle Cell Disease. Among its related pathways are …

Ecto-ADP-ribosyltransferase 4 is an enzyme that in humans is encoded by the ART4 gene. [5][6] ART4 has also been designated as CD297 (cluster of differentiation 297). This gene encodes a protein that contains a mono-ADP-ribosylation (ART) motif.

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2005年9月25日 · Mono-ADP-ribosyltransferase (ART) 4 belongs to a family of ectoenzymes that catalyze the transfer of ADP-ribose from NAD + to a target protein. ART4 could be detected on HEL cells and erythrocytes by FACS analysis while it was absent from activated monocytes, despite the presence of ART4 mRNA in these cells.

2024年11月2日 · Title: Sequencing of the ART4 gene in sub-Saharan cohorts reveals ethnic differences and two new DO alleles: DO*B-Ile5Thr and DO*B-Trp266Arg. The production, serologic evaluation, and epitope mapping of ten murine monoclonal Dombrock antibodies.

Gene ID: 420, updated on 8-Feb-2025. This gene encodes a protein that contains a mono-ADP-ribosylation (ART) motif. It is a member of the ADP-ribosyltransferase gene family but enzymatic activity has not been demonstrated experimentally.

2025年2月8日 · Clinical resource with information about ART4, Blood group, Dombrock system, and available tests. There are links to practice guidelines and authoritative resources like GeneReviews, PubMed, MedlinePlus, PharmGKB and clinicaltrials.gov.

该基因编码的蛋白质包含单-ADP-核糖基化 (ART) 基序。 它是 ADP-核糖基转移酶基因家族的成员，但酶活性尚未通过实验证明。 Dombrock 血型系统的抗原位于基因产物上，该基因产物是锚定在红细胞膜上的糖基磷脂酰肌醇。 已知等位基因变异，其中一些会导致不良输血反应。 [RefSeq 提供，2008 年 7 月] This gene encodes a protein that contains a mono-ADP-ribosylation (ART) motif.