Lifestyle intervention designed to manage body weight and treat obesity, as well as patient education, are essential for all patients with diabetes. Treatment options may be individualized and medication(s) chosen based on a patient’s risk factors, current HbA1C level, medication efficacy, ease of use, patient’s financial situation ...

Antidiabetic agents refer to all the different types of medicine involved in the treatment of diabetes. All these agents aim to reduce blood sugar levels to an acceptable range (called achieving normoglycemia) and relieve symptoms of diabetes such as thirst, excessive urination, and ketoacidosis (a serious complication of diabetes that occurs ...

2005年10月4日 · Several classes of type 2 diabetes medicines exist. Each class of medicine works in a different way to lower blood sugar. A medication may work by: Causing the pancreas to make and release more insulin. Limiting the liver's ability to make and release sugar.

Drugs used in diabetes treat types of diabetes mellitus by decreasing glucose levels in the blood. With the exception of insulin, most GLP-1 receptor agonists (liraglutide, exenatide, and others), and pramlintide, all diabetes medications are administered orally and are thus called oral hypoglycemic agents or oral antihyperglycemic agents ...

2022年7月28日 · The cornerstone of treatment of type 2 diabetes is comprehensive lifestyle education. This includes diabetes self-management education and support (DSMES), medical nutrition therapy, routine physical activity, smoking cessation counseling, and psychosocial care.

To provide an up-to-date account of the current trends of antidiabetic pharmaceuticals, this review offers a comprehensive analysis of the main classes of antihyperglycemic compounds and their mechanisms: insulin types, biguanides, sulfonylureas, meglitinides (glinides), alpha-glucosidase inhibitors (AGIs), thiazolidinediones (TZD), incretin-dep...

2018年1月1日 · SUs should be considered as drugs of choice for the treatment of diabetes considering their safety, efficacy, low cost of therapy, and pleiotropic benefits. 22 Efficacy SUs act mainly by augmenting insulin secretion and consequently are effective only when some residual pancreatic β-cell activity is present.

The main goals of Anti diabetes therapy are to reduce symptoms of hyperglycaemia and to reduce the risk of long-term complications of diabetes. GC, using glycosylated haemoglobin (HbA1c) as a marker, is known to reduce the risk for microvascular complications, including retinopathy and neuropathy [ 5 - 7 ].

2023年12月5日 · Combined therapies emphasizing early and sustained glycemic control are promising options for diabetes management. As insulin therapy remains pivotal, metformin and non-insulin agents such as GLP-1 RA and SGLT-2i offer compelling options.

2024年2月16日 · Antidiabetic drugs (except insulin) are all pharmacological agents that have been approved for hyperglycemic treatment in type 2 diabetes mellitus (DM). If lifestyle modifications (weight loss, die...