Allograft inflammatory factor 1 (AIF-1) also known as ionized calcium-binding adapter molecule 1 (IBA1) is a protein that in humans is encoded by the AIF1 gene. [5][6] The AIF1 gene is …

2024年12月24日 · AIF1 (Allograft Inflammatory Factor 1) is a Protein Coding gene. Diseases associated with AIF1 include Nonarteritic Anterior Ischemic Optic Neuropathy and Traumatic …

Iba1是细胞骨架结合蛋白，促进细胞膜运动与RAC激活，并在RAC信号通路及吞噬过程中发挥作用。 Iba1促进血管平滑肌细胞及T淋巴细胞增殖，促进淋巴细胞迁移，在巨噬细胞激活与功能中 …

Allograft inflammatory factor 1 (AIF1) is a calcium-binding protein that participates in intracellular processes such as phagocytosis, membrane ruffling and F-actin remodeling. Due to its …

2025年3月1日 · AIF-1 induces VSMCs to dedifferentiate into macrophage-like cells, enhancing lipid uptake and inflammatory factor secretion through the PKC/NF-κB pathway. Inhibiting AIF …

The allograft inflammatory factor-1 (AIF-1) is a 17 kDa interferon-gamma (IFN-gamma) inducible Ca (2+)-binding EF-hand protein that is encoded within the HLA class III genomic region. …

同种异体移植炎症因子1 (allograft inflammatory factor 1，AIF 1)是从慢性排斥的心脏移植物中克隆的一种高度保守的炎症反应支架蛋白,通过调节细胞因子、趋化因子和诱导型一氧化氮合酶等 …

该基因编码一种结合肌动蛋白和钙的蛋白质。 该基因由细胞因子和干扰素诱导，可促进巨噬细胞活化和血管平滑肌细胞和 T 淋巴细胞的生长。 该基因的多态性可能与系统性硬化症有关。 可变 …

aif-1,同种异体移植物炎症因子,是由143个氨基酸组成的含有一个ef螺旋结构的细胞质的钙结合蛋白,相对分子质量为17 000,它编码在hla-Ⅲ基因的6号染色体上.aif-1从大鼠和人的发生慢性移植排 …

AIF-1 boosts the expression of inflammatory mediators such as cytokines, chemokines, inducible nitric oxide synthase (iNOS) and promotes inflammatory cell proliferation and migration. Here …