Duffy antigen/chemokine receptor (DARC), also known as Fy glycoprotein (FY) or CD234 (Cluster of Differentiation 234), is a protein that in humans is encoded by the ACKR1 gene. [5] [6] [7] …

2024年12月24日 · ACKR1 (Atypical Chemokine Receptor 1 (Duffy Blood Group)) is a Protein Coding gene. Diseases associated with ACKR1 include White Blood Cell Count Quantitative …

Atypical chemokine receptor 1 (ACKR1), previously known as the Duffy antigen receptor for chemokines (DARC), is a key regulator that binds chemokines involved in inflammatory …

2024年9月20日 · The ACKR1 gene encodes the Duffy antigen receptor for chemokines (DARC), which is expressed on red blood cells (RBCs), endothelial cells, and other cell types.

2025年3月8日 · Title: Endothelial ACKR1 is induced by neutrophil contact and down-regulated by secretion in extracellular vesicles. Presence of ""ACKR1/DARC null"" polymorphism in Arabs …

2024年12月18日 · Targeting ACKR1 through both functional and pharmacological approaches effectively suppressed TAAD progression and extended survival in TAAD mice, offering …

2013年10月11日 · Atypical chemokine receptors (ACKRs) are structurally related to conventional chemokine receptors but are unable to initiate classical chemokine receptor signalling after …

2024年5月7日 · There are four receptors currently with formal ACKR designation: ACKR1 (formerly known as Duffy antigen receptor for chemokines (DARC)), ACKR2 (formerly known …

2024年9月24日 · Genome-wide association replicates the association of Duffy antigen receptor for chemokines (DARC) polymorphisms with serum monocyte chemoattractant protein-1 (MCP …

Tumor-specific immune response is an important aspect of disease prognosis and ultimately impacts treatment decisions for innovative immunotherapies. The Atypical Chemokine …