2024年12月24日 · ADRB2 (Adrenoceptor Beta 2) is a Protein Coding gene. Diseases associated with ADRB2 include Asthma and Nocturnal Asthma. Among its related pathways are Activation of cAMP-Dependent PKA and Class A/1 (Rhodopsin-like receptors). Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and enzyme binding.

ADRB2 consists of a single exon of 2015 nucleotides, which encodes a 413 amino acid protein. This review highlights the genetic polymorphisms in ADRB2 and the pivotal role of beta2- AR in the regulation of the cardiac, pulmonary, vascular, endocrine, and central nervous systems.

The beta-2 adrenergic receptor (ADRB2) is an important target for epinephrine, a neurotransmitter in pain signalling. ADRB2 haplotypes affect receptor expression and ligand response, and have been linked to painful non-GI disorders.

Adrenergic receptor β 2 (ADRB2) is a primary target for epinephrine. It plays a critical role in mediating physiological and psychological responses to environmental stressors. Thus, functional genetic variants of ADRB2 will be associated with a complex array of psychological and physiological phenotypes.

2020年11月20日 · Both innate and adaptive immune cells express adrenergic receptors, primarily the β2-adrenergic receptor (ADRB2), enabling them to directly respond to the sympathetic nervous system . Sympathetic nerves secrete NE in response to …

2020年1月17日 · The ADRB2 gene, located on chromosome 5q31-q32 and encoding for the β-2 AR with 413 amino acids, has more than 80 SNPs identified within its coding region. The mutation that results in the amino acid change at codon 16, where neutral glycine is substituted for basic arginine, is located within the N-terminus of the β-2 AR.

2022年9月26日 · ADRB2 expression in LUAD was significantly correlated with gender, smoking status, T classification, and pathologic stage. Patients in the low ADRB2 expression group presented with...

2024年11月27日 · This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca (V)1.2.

Gene ID: 154, updated on 8-Feb-2025. This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca (V)1.2.

2025年1月4日 · Title: The association of gene polymorphisms in catechol-O'methyltransferase (COMT) and β2-adrenergic receptor (ADRB2) with temporomandibular joint disorders. Association between the Ile164 beta2 Adrenergic Receptor Polymorphism and Fatigue in Patients with Rheumatoid Arthritis.