ABL2 is a cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of the proteins includes the tyrosine kinase domains and extends amino-terminal to …

2024年12月24日 · ABL2 (ABL Proto-Oncogene 2, Non-Receptor Tyrosine Kinase) is a Protein Coding gene. Diseases associated with ABL2 include Leukemia, Acute Lymphoblastic and …

The Abelson tyrosine kinases were initially identified as drivers of leukemia in mice and humans. The Abl family kinases Abl1 and Abl2 regulate diverse cellular processes during development …

The Abelson (ABL) family of nonreceptor tyrosine kinases, ABL1 and ABL2, transduces diverse extracellular signals to protein networks that control proliferation, survival, migration, and …

2025年2月19日 · A 35-bp insertion in the BCR-ABL2 gene is associated with resistance to tyrosine kinase inhibitors, but sensitivity to omacetaxine in chronic myelogenous leukemia. …

Abl-targeting drugs serve as a paradigm for our understanding of kinase inhibitor action, specificity, and resistance development. In this review article, I will review the molecular …

2024年10月6日 · Clinical resource with information about ABL2, A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction …

ABL proto-oncogene 2, non-receptor tyrosine kinase (ABL2) is a gene that encodes a protein non-receptor tyrosine kinase. The protein functions in cytoskeletal rearrangements.

ABL2 - Explore an overview of ABL2, with a histogram displaying coding mutations, full tabulated details of all associated variants, tissue distribution and any drug resistance data.

BACKGROUND: Diseases associated with Abelson-related gene (also called ABL2) include leukemia; furthermore, previous researches have studied the expressions and functions of …