2015年9月14日 · Wnt3a, one of Wnt family members, plays key roles in regulating pleiotropic cellular functions, including self-renewal, proliferation, differentiation, and motility. Accumulating evidence has suggested that Wnt3a promotes or suppresses tumor progression via the canonical Wnt signaling pathway depending on cancer type.

Wnt3a, one of Wnt family members, plays key roles in regulating pleiotropic cellular functions, including self-renewal, proliferation, differentiation, and motility. Accumulating evidence has suggested that Wnt3a promotes or suppresses tumor ...

2024年12月25日 · WNT3A (Wnt Family Member 3A) is a Protein Coding gene. Diseases associated with WNT3A include Hypophosphatasia, Adult and Short Stature And Advanced Bone Age With Or Without Early-Onset Osteoarthritis And/Or Osteochondritis Dissecans.

2022年1月3日 · Three key signalling molecules in the Wnt/β-catenin signalling pathway—Wnt3a, β-catenin, and Cyclin D1—are upregulated at the mRNA and protein levels in the adult spinal cord of SOD1...

2015年9月14日 · Herein, we summarize the latest findings on Wnt3a as an important therapeutic target in cancer. Wnt3a, one of Wnt family members, plays key roles in regulating pleiotropic cellular functions, including self-renewal, proliferation, differentiation, and motility.

WNT3A is a component of the Wnt/β-catenin signaling pathway, which is involved in cell-cell adhesion as well as stimulation of oncogenic factors such as c-Myc and CCND1.

2019年6月24日 · Wnt3a is an attractive candidate target for therapeutic intervention in the pathogenesis of cancer. In this review, we summarized roles of the Wnt3a ligand in the pathogenesis of different cancers including colorectal, prostate, hepatocellular carcinoma, lung cancer and leukemia.

2015年9月14日 · Wnt3a, one of Wnt family members, plays key roles in regulating pleiotropic cellular functions, including self-renewal, proliferation, differentiation, and motility. Accumulating evidence has suggested that Wnt3a promotes or suppresses tumor progression via the canonical Wnt signaling pathway depending on cancer type.

2025年2月8日 · Wnt3a induces canonical and non-canonical Wnt signaling in HUVECs, and stimulates their proliferation and migration. The presence of WNT3a completely prevents normal adipocyte differentaiton.

2025年2月8日 · Gene target information for WNT3A - Wnt family member 3A (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.