The very-low-density-lipoprotein receptor (VLDLR) is a transmembrane lipoprotein receptor of the low-density-lipoprotein (LDL) receptor family. VLDLR shows considerable homology with the members of this lineage. Discovered in 1992 by Tokuo. Yamamoto and Sadao.

2024年12月25日 · VLDLR (Very Low Density Lipoprotein Receptor) is a Protein Coding gene. Diseases associated with VLDLR include Cerebellar Ataxia, Impaired Intellectual Development, And Dysequilibrium Syndrome 1 and Congenital Nervous System Abnormality.

2021年12月20日 · We show that the E2 and E1 glycoproteins (E2–E1) of Semliki forest virus, eastern equine encephalitis virus and Sindbis virus interact with the ligand-binding domains (LBDs) of VLDLR and...

VLDL cholesterol is a “bad” form of cholesterol because, in excess, it causes plaque buildup (atherosclerosis) in your arteries. A normal VLDL level is below 30 mg/dL. Your healthcare provider can measure your VLDL cholesterol through a simple blood test. If your VLDL is high, lifestyle changes and medication can help. What is VLDL?

2021年4月13日 · Very low-density lipoprotein receptor (VLDLR) is a member of the LDL receptor family that is involved in the uptake of VLDL into cells. Increased hepatic VLDLR under endoplasmic reticulum...

VLDLR functions as a negative regulator of CNV, and this function is mediated through the wnt pathway. Homozygous deletion of the very low density lipoprotein receptor gene causes autosomal recessive cerebellar hypoplasia with cerebral gyral simplification.

1998年3月24日 · There are many candidate receptors for the lipid accumulation, such as LDL receptor (LDLR), VLDL receptor (VLDLR), LDL receptor-related protein (LRP), and scavenger receptors (SRs). However, little quantitative information exists on the expression of these receptors in normal and atherosclerotic arteries.

2024年12月10日 · This gene encodes a lipoprotein receptor that is a member of the LDLR family and plays important roles in VLDL-triglyceride metabolism and the reelin signaling pathway. Mutations in this gene cause VLDLR-associated cerebellar hypoplasia. Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene.

The VLDLR gene provides instructions for making a protein called a very low density lipoprotein (VLDL) receptor. This protein is active in many different organs and tissues, including the heart, muscles used for movement (skeletal muscles), fatty (adipose) tissue, and the kidneys.

2024年10月22日 · Using a targeted CRISPR-Cas9 survival screen, Palakurty et al. identify the very-low-density lipoprotein receptor (VLDLR) as a receptor for Western equine encephalitis virus (WEEV) and other related viruses in its antigenic complex.