There are two types of large granular lymphocytic leukemia: T-cell large granular lymphocytic leukemia (T-LGL) and chronic lymphoproliferative disorder of NK cells (CLPD-NK). These conditions start in white blood cells called cytotoxic T cells or natural killer cells .

There are two types of LGL leukemia: T-cell (T-LGL) and natural killer cell (NK-LGL). Each type may be chronic (slow-growing) or aggressive (fast-growing). The frequency of T-cell and NK-cell LGL leukemia ranges from 2 to 5 percent of chronic lymphoproliferative diseases.

2017年3月2日 · Indolent T-LGL leukemia is the most frequent form of the disease representing ∼85% of the cases, whereas chronic NK-cell lymphocytosis is estimated at <10% of cases. Aggressive NK-LGL leukemia is mainly seen in Asia and comprises <5% of the LGL disorders.

T-cell large granular lymphocyte leukemia causes a slow increase in white blood cells called T lymphocytes, or T cells, which originate in the lymph system and bone marrow and help to fight infection.

Large granular lymphocytic (LGL) leukemia is a chronic lymphoproliferative disorder that exhibits an unexplained, chronic (> 6 months) elevation in large granular lymphocytes (LGLs) in the peripheral blood. [1] It is divided in two main categories: T-cell LGL leukemia (T-LGLL) and natural-killer (NK)-cell LGL leukemia (NK-LGLL).

2011年3月10日 · Large granular lymphocyte (LGL) leukemia is characterized by a clonal expansion of either CD3 + cytotoxic T or CD3 − NK cells. Prominent clinical features of T-LGL leukemia include neutropenia, anemia and rheumatoid arthritis (RA).

Large granular lymphocyte leukemia is chronic lymphocytic leukemia. It has two types: T-cell large granular lymphocytic leukemia (T-LGL). Chronic lymphoproliferative disorder of NK-cells (CLPD-NK), also known as chronic NK cell lymphocytosis and aggressive NK cell leukemia.

T-cell large granular lymphocytic leukemia (T-LGL leukemia) is a rare and chronic form of leukemia that affects T-cells, a type of white blood cell crucial for the immune system’s ability to fight infections.

Roughly 85% of reported LGL leukemia cases are the T-LGL subtype, with less than 10% of cases described as chronic NK-LGL leukemia. The aggressive NK-cell disease typically presents in young Asian populations with Epstein Barr virus …

2023年3月29日 · This article examines T-LGL and its symptoms, risk factors, diagnosis, and treatment. It also discusses the outlook for T-LGL leukemia.