2024年12月25日 · SOX1 (SRY-Box Transcription Factor 1) is a Protein Coding gene. Diseases associated with SOX1 include Lambert-Eaton Myasthenic Syndrome and Bilateral Hypoactive …

SOX1 is one of the earliest TFs expressed in cells committed to the neural fate. Its expression correlates with the formation of neural plate, while down-regulation of Sox1 expression in the …

Anti-Sry-like high mobility group box (SOX) 1 antibodies (abs) are partly characterized onconeural autoantibodies (autoabs) due to their correlation with neoplastic diseases. Anti-SOX1 abs are …

This review systematically explores the reported patients with anti-SOX1 abs and analyzes these cases for demographic characteristics, clinical features, coexisting neuronal autoabs, …

We demonstrate a role for SOX1 in neural determination and differentiation using an inducible expression P19 cell system as an in vitro model of neurogenesis. Misexpression of SOX1 can …

SOX1 plays many roles in embryogenesis, oncogenesis, and male sex determination, and can promote glioma stem cell proliferation, invasion, and migration due to its high expression in …

First, most Sox factors are expressed in multiple types of stem/progenitor cell types or tissues. Second, many Sox factors act redundantly in the maintenance of stem cells (e.g., Sox1, Sox2, …

Data show that high levels of SRY-box transcription factor 1 (SOX1) observed in a subset of patients correlate with lower overall survival, and suggest SOX1 as a potential target in the …

2004年5月15日 · Overexpression of Sox1 in neural cell lines activates the expression of the proneural gene neurogenin1 and promotes exit from cell cycle and neuronal differentiation.

2020年9月9日 · Our study uncovers that SOX1 is required for the specification of NPCs with the rostral hindbrain identity from hESCs primarily by directly promoting GBX2 expression.