SDHB is one of four protein subunits forming succinate dehydrogenase, the other three being SDHA, SDHC and SDHD. The SDHB subunit is connected to the SDHA subunit on the …

2025年1月28日 · Our mission is to educate healthcare professionals and patients on the SDHB genetic germline mutation as well as its role and impact in this orphan disease, namely …

The SDHB gene provides instructions for making one of four subunits of the succinate dehydrogenase (SDH) enzyme. The SDH enzyme plays a critical role in mitochondria, which …

Research into the SDHB gene has revealed several important findings: Essential Functions: The SDHB gene encodes for a subunit of the enzyme succinate dehydrogenase, crucial for the …

2008年5月21日 · Evaluation of relatives at risk: First-degree relatives of an individual with a hereditary PGL/PCC syndrome and a known MAX, SDHA, SDHAF2, SDHB, SDHC, SDHD, or …

2024年12月11日 · What is my cancer risk if I have an SDHB mutation? If you have a mutation in the SDHB gene, this means you have a condition called hereditary paraganglioma …

2024年12月25日 · This tumor suppressor gene encodes the iron-sulfur protein subunit of the succinate dehydrogenase (SDH) enzyme complex which plays a critical role in mitochondria. …

Pheochromocytoma can be a solitary disease affecting only the adrenal gland, and in other situations they can develop alongside paraganglioma in some genetic mutations, such as …

Mutations in the SDHx genes (SDHA, SDHB, SDHC and SDHD), which encode the four subunits of the mitochondrial enzyme succinate dehydrogenase (SDH), are associated with a …

Pheochromocytoma can be a solitary disease affecting only the adrenal gland, and in other situations they can develop alongside paraganglioma in some genetic mutations, such as …