Rac2 (Ras-related C3 botulinum toxin substrate 2) is a small (~21 kDa) signaling G protein (to be specific, a GTPase), and is a member of the Rac subfamily of the family Rho family of …

Ras-related C3 botulinum toxin substrate 2 (Rac2) is a 21 kDa GTPase encoded by 192 amino acids that acts as a molecular switch in a variety of cellular events that include cell motility, …

2024年12月25日 · RAC2 (Rac Family Small GTPase 2) is a Protein Coding gene. Diseases associated with RAC2 include Immunodeficiency 73A With Defective Neutrophil Chemotaxis …

2022年6月8日 · We have carried out conditional gene targeting to achieve hematopoietic stem cell (HSC)– or T-cell lineage–specific deletion of Rac1 or Rac1/Rac2 by crossbreeding the Mx …

Circulating neutrophils are persistently higher in mice deficient in the small GTPase Rac2 than in wild-type (WT) mice. Therefore, we examined the mechanisms through which the small …

A gain-of-function RAC2 mutation is associated with bone-marrow hypoplasia and an autosomal dominant form of severe combined immunodeficiency. The Rac2 GTPase contributes to …

2025年2月9日 · Title: A gain-of-function RAC2 mutation is associated with bone-marrow hypoplasia and an autosomal dominant form of severe combined immunodeficiency. The Rac2 …

2024年4月11日 · Twenty-three distinct RAC2 mutations, including 15 novel variants, were identified. Using heterologous expression systems, we assessed downstream effector …

2020年8月17日 · The RAC2 gene encodes a member of the RHO family of GTPases, which are a group of cellular signaling molecules that bind downstream effectors to activate a variety of …

2025年2月23日 · RAC2 is a me … Several molecular pathways are likely involved in the regulation of cancer stem cells (CSCs) via Ras-associated C3 botulinum toxin substrate 2, …