Peroxisome proliferator-activated receptor alpha (PPAR-α), also known as NR1C1 (nuclear receptor subfamily 1, group C, member 1), is a nuclear receptor protein functioning as a transcription factor that in humans is encoded by the PPARA gene. [5]

2024年12月25日 · PPARA (Peroxisome Proliferator Activated Receptor Alpha) is a Protein Coding gene. Diseases associated with PPARA include Liver Disease and Steatotic Liver Disease. Among its related pathways are Transcriptional regulation of white adipocyte differentiation and Circadian Clock.

In the field of molecular biology, the peroxisome proliferator–activated receptors (PPARs) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes. [1] .

Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as …

PPARA is a receptor for peroxisome proliferators such as hypolipidaemic drugs and fatty acids, regulating the peroxisomal beta-oxidation pathway of fatty acids and acting as a transcription activator for ACOX1 and P450.

Peroxisome proliferator-activated receptor α (PPARα) is a nuclear receptor expressed in many tissues and is responsible for several important metabolic controls, especially during fasting. PPARα is a target for the hypolipidemic drugs of the fibrate family.

Peroxisome proliferators are a diverse group of chemicals which includes hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers.

Peroxisome proliferator-activated receptor alpha (PPARA) is a plateau-adapted gene that regulates respiratory function in populations adapted to high-altitude areas through multiple pathways. Interestingly, PPARA expression is higher in long-term inhabiting Tibetan populations that have adapted to the plateau environment.

Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as a …

Peroxisome proliferator-activated receptor alpha (PPARA) is a ligand-activated transcription factor that is abundantly expressed in liver. PPARA is activated by fatty acids and various other lipid species, as well as by a class of chemicals referred to as peroxisome proliferators.