2009年7月1日 · PfEMP1 was shown to be a key molecule in defining the cytoadhesive properties of the iRBC to neighboring uninfected RBCs, forming structures called rosettes, as well as …

2023年5月8日 · During the evolutionary arms race between the Plasmodium parasite and humankind, P. falciparum has evolved strategies to antagonize the function of IgM. …

2001年11月15日 · The malarial protein Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is a parasite protein that is exported to the surface of the infected erythrocyte, where …

The Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family has a key role in parasite survival, transmission, and virulence. PfEMP1 are exported to the erythrocyte …

2015年4月1日 · PfEMP1 plays an important role in P. falciparum rosetting, which is a diverse adhesion phenotype that appears to involve multiple PfEMP1 ligands and several erythrocyte …

In this review, we will focus on the role of the P. falciparum membrane protein 1 (PfEMP1) family of VSA as targets of naturally acquired immunity and review their potential as vaccine targets. …

Among several proteins and protein families implicated in this process, the P. falciparum erythrocyte membrane protein 1 (PfEMP1) family of high-molecular weight and highly variable …

We investigated the immunosuppressive effect of PfEMP1 on monocytes/macrophages, which are central to the antiparasitic innate response. RAW macrophages and human primary …

We are studying the role of Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) expressed by asexual stages of P. falciparum responsible for the pathogenicity of severe …

As the antibody response against the single expressed PfEMP1 develops, small sub-populations of parasites switch expression to alternative forms of PfEMP1 and re-establish the infection. …