2008年6月19日 · PLA2G6 -associated neurodegeneration (PLAN) comprises a continuum of three phenotypes with overlapping clinical and radiologic features: INAD usually begins between …

PLA2G6-associated neurodegeneration (PLAN) is a neurodegenerative disorder associated with iron accumulation in the brain, primarily in the basal ganglia. It is characterized by progressive …

2022年6月14日 · PLA2G6-associated neurodegeneration (PLAN) is an extremely rare, inherited degenerative disorder of the nervous system characterized by abnormalities of nerve endings …

2024年12月25日 · PLA2G6 (Phospholipase A2 Group VI) is a Protein Coding gene. Diseases associated with PLA2G6 include Neurodegeneration With Brain Iron Accumulation 2A and …

PLA2G6-associated neurodegeneration (PLAN) is a complex group of neurodegenerative diseases that result from mutations in a gene known as PLA2G6. According to the age of …

The PLA2G6 gene provides instructions for making a type of enzyme called an A2 phospholipase. Learn about this gene and related health conditions.

2023年8月1日 · PLA2G6 is involved in neurodegenerative diseases pathology with abnormal lipid metabolism and protein-protein interactions. Genetic test may reveal more PLA2G6 variants, …

PLAN is caused by variants in the phospholipase A2 group VI gene (PLA2G6), which encodes an enzyme involved in membrane homeostasis, signal transduction, mitochondrial dysfunction, …

Introduction: PLA2G6-associated neurodegeneration (PLAN) comprises a continuum of three phenotypes with overlapping clinical and radiologic features. Methods: Observational clinical …

2023年7月5日 · Phospholipase-associated neurodegeneration (PLAN) caused by mutations in the PLA2G6 gene is a rare neurodegenerative disorder that presents with four sub-groups. …