2024年12月25日 · NSD1 (Nuclear Receptor Binding SET Domain Protein 1) is a Protein Coding gene. Diseases associated with NSD1 include Sotos Syndrome and Beckwith-Wiedemann …

The NSD1 gene provides instructions for making a protein that functions as a histone methyltransferase. Histone methyltransferases are enzymes that modify structural proteins …

Recurrent epigenomic alterations associated with multiple human pathologies have increased the interest in the nuclear receptor binding SET domain protein 1 (NSD1) lysine …

2024年2月13日 · NSD1 is a histone methyltransferase that catalyzes histone H3 lysine 36 di-methylation (H3K36me 2); mutations inactivating NSD1 have been linked to improved …

An in-depth study of the structure and biological activities of NSD1 sets the groundwork for improving tumor therapy and creating NSD1 inhibitors. This article emphasizes the role of …

HGNC Approved Gene Symbol: NSD1. Cytogenetic location: 5q35.3 Genomic coordinates (GRCh38) : 5:177,131,798-177,300,213 (from NCBI) The androgen receptor (AR; 313700) is a …

2023年12月26日 · NSD1 loss in the neocortex causes behavior defects relevant to Sotos syndrome. NSD1-mediated H3K36me2 shapes the DNA methylation landscape, facilitating the …

2021年7月14日 · Here, we review the current knowledge about the biochemistry, cellular function and role of NSD1 in human diseases. Several studies have shown that NSD1 controls gene …

Gene ID: 64324, updated on 8-Feb-2025. This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger …

The NSD1 gene provides instructions for making a protein that functions as a histone methyltransferase. Histone methyltransferases are enzymes that modify structural