The life expectancy of a person with NF is approximately 8 years less than that of the general population. Lifetime risks of both benign and malignant tumors are increased in individuals with neurofibromatosis type 1 (NF1).

2025年2月13日 · While NF1 is rare, it is the most common type of NF. Symptoms can develop slowly, so getting the correct diagnosis may take several years. But most people are diagnosed during early childhood. Most people with NF1 have an average life expectancy.

A 12-year follow-up of 70 adult patients with NF1 (Zöller et al. 1995) found a decrease in life expectancy of ∼15 years. Malignancy was the cause of death for more than half the patients, and hypertension was significantly associated with mortality.

Neurofibromatosis type 1 (also called Von Recklinghausen’s disease, Von Recklinghausen neurofibromatosis and peripheral NF) is one of the most commoninherited disorders and affects about one in every 3,000 people. NF1 ranges from mild to severe, and can cause more symptoms in some people than in others.

2021年4月20日 · Researchers have estimated that such malignant cancers decrease the life expectancy of people with NF1 by an average of 10 to 15 years. But because NF1 itself is relatively rare, researchers have struggled to assemble a comprehensive picture of …

2023年11月20日 · What is the life expectancy of someone with neurofibromatosis? Neurofibromatosis doesn’t usually affect your life expectancy. The location of the tumors can make certain aspects of your daily routine difficult without assistance, like …

About 1 in 2,500 is affected by NF1. The tumors often are not cancerous, known as benign tumors. But sometimes they can become cancerous. Symptoms often are mild. But complications can occur and may include trouble with learning, heart …

2012年9月21日 · I've read that patients with neurofibromatosis 1 may have reduced life expectancy by up to 15 years, usually due to malignant tumors [which, because it mostly happens with young patients, skews life expectancy downwards] or untreated / uncontrolled BP.

In order to gain insights into these aspects, we have conducted a 12-year follow-up study of 70 adult NF1 patients in the city of Göteborg, Sweden, whereby life expectancy, mortality, causes of death and the prognostic value of clinical findings were investigated.

2021年3月9日 · If there are no complications, the life expectancy of patients with neurofibromatosis tends to be lower than in the general population with 10 to 15 years. Prompt diagnosis and treatment of the symptoms may improve life expectancy to more than 15 years following diagnosis.