The MMAB gene provides instructions for making an enzyme that is involved in the formation of a compound called adenosylcobalamin (AdoCbl). Learn about this gene and related health …

PDBe-KB provides an overview of all the structure information available in the PDB for Human Corrinoid adenosyltransferase (MMAB)

2024年12月25日 · MMAB (Metabolism Of Cobalamin Associated B) is a Protein Coding gene. Diseases associated with MMAB include Methylmalonic Aciduria, Cblb Type and …

Methylmalonic acidemia (cobalamin disorders) is caused by changes in either the MMAA or MMAB gene. The MMAA and MMAB genes give your body instructions for proteins that are …

2021年11月8日 · We demonstrate that hepatic levels of MMAB are modulated by dietary and cellular cholesterol levels through SREBP2, the master transcriptional regulator of cholesterol …

Methylmalonic acidemia (MMA) is a lethal, severe heterogeneous disorder of methylmalonate and cobalamin (cbl; vitamin B12) metabolism with poor prognosis.

At least 25 mutations in the MMAB gene have been found to cause methylmalonic acidemia, a condition characterized by feeding difficulties, developmental delay, and long-term health …

2023年10月24日 · The MMAB gene encodes cob(I)alamin adenosyltransferase (EC 2.5.1.17), which catalyzes the final step in the synthesis of the cofactor adenosylcobalamin (AdoCbl).

2016年11月1日 · Go to Variation Viewer for MMAB variants Summary This gene encodes a protein that catalyzes the final step in the conversion of vitamin B(12) into adenosylcobalamin …

2021年11月8日 · We demonstrate that hepatic levels of MMAB are modulated by dietary and cellular cholesterol levels through SREBP2, the master transcriptional regulator of cholesterol …