Interstitial collagenase, also known as fibroblast collagenase and matrix metalloproteinase-1 (MMP-1), is an enzyme that in humans is encoded by the MMP1 gene. [1][2][3][4] The gene is …

MMP-1 is elevated in women with PE, but without an increase in TIMP-1. It is involved in the degradation of vascular collagen type I, which increases vascular permeability and favors …

MMP-1 catalytic domain, hemopexin-like domain and linker. The hemopexin-like domain has four β-propeller structural elements [8, 12, 13, 17]. This domain is necessary for collagen triple …

Matrix metalloproteinases (MMPs), also known as matrix metallopeptidases or matrixins, are metalloproteinases that are calcium -dependent zinc -containing endopeptidases; [1] other …

2024年12月25日 · MMP1 (Matrix Metallopeptidase 1) is a Protein Coding gene. Diseases associated with MMP1 include Recessive Dystrophic Epidermolysis Bullosa and Pulmonary …

Human fibroblast collagenase (MMP-1) was the first vertebrate collagenase purified as a protein and cloned as a cDNA, and is considered the prototype for all the interstitial collagenases.

MMP-1 or collagenase-1 was the first described matrix metalloprotease and has sparked a large volume of research on the physiological and pathological role of MMPs.

MMP-1, or interstitial collagenase, is present in aggressive tumors, suggesting a correlation between MMP-1 and poor prognosis [59,140–145]. MMP-1 is probably not a major player in …

2024年9月3日 · MMP-1, also known as human fibroblast collagenase, was the first vertebrate collagenase to be purified and cloned, making it the prototype for interstitial collagenases. It is …

2025年2月8日 · Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue …