Lisch nodules are melanocytic hamartomas of the iris, often associated with neurofibromatosis (NF) I. They are usually elevated and tan in appearance. Their incidence in NF1 increases with age and their prevalence raises by about 10% per year of life, up to age 9.

2005年5月15日 · For the ophthalmologist, NF1 may present with a variety of ophthalmic manifestations. Lisch nodules (melanocytic nevi of the iris and uveal tract) are the most common finding. Development of a plexiform neurofibroma within the lid can cause a classic S-shaped ptosis in the pediatric patient. Optic nerve gliomas occur in 12% of patients with NF1 ...

2008年2月8日 · Neurofibromatosis type 1 (NF-1) Lisch Nodules. Ophthalmology Case Reports and Grand Rounds from the University of Iowa Department of Ophthalmology & Visual Sciences

Iris mammillations are diffuse, tiny, nodules that cover the iris surface. They are most commonly unilateral and are usually seen in darkly pigmented irides or overlying iris nevi. Mammillations can be associated with oculodermal melanocytosis or phakomatosis pigmentovascularis (PPV) type IIb and neurofibromatosis (NF) type I.

Category(ies): Glaucoma, Iris Contributor: Jesse Vislisel, MD Photographer: Antoinette Venckus, CRA. Kunkmann-Wolffian bodies are hypopigmented areas of peripheral iris stromal hyperplasia in patients without Down syndrome. They are clinically indistinguishable from Brushfield spots which are seen in individuals with Down syndrome.

Title: Atlas Entry - Lisch nodules Author: brettjohnson Created Date: 8/15/2019 1:41:30 PM

2018年7月20日 · Cogan-Reese syndrome is unique among the ICE syndromes due to the presence of pedunculated, pigmented iris nodules, commonly referred to as iris nevi [1]. The classic Cogan-Reese nodules, which result from melanocytic proliferation within the iris stroma, are present on the anterior surface of the iris, appear late in the disease, and become ...

This is a 78-year-old man with neurofibromatosis type 1. He has multiple Lisch nodules. He was diagnosed with open angle glaucoma at age 74. Courtesy of Young H. Kwon, MD, PhD. The University of Iowa.

2005年2月21日 · Cogan-Reese syndrome: pigmented nodules on iris. Essential iris atrophy: corectopia, stretch & melt holes. Abnormal corneal endothelial cells act like epithelial cells and may grow into the angle to block trabecular meshwork outflow. PAS formation in the angle. SYMPTOMS Asymptomatic early in disease.

2017年12月20日 · The origin of these microhemangiomas is presumed to originate in the capillary network, which marks the end of the radial vessels and surrounds the sphincter of the iris [1]. Most patients with vascular tufts of the pupillary margin have no systemic disease, but they are also found in patients with diabetes mellitus and myotonic dystrophy [2].