ISL1 is a marker for cardiac progenitors of the secondary heart field (SHF) which includes the right ventricle and the outflow tract. The biological function of ISL1 is demonstrated through …

2024年12月25日 · ISL1 (ISL LIM Homeobox 1) is a Protein Coding gene. Diseases associated with ISL1 include Bladder Exstrophy and Double Outlet Right Ventricle. Among its related …

Isl1, a LIM-homeodomain transcription factor, acts as a key player in multiple organs during embryonic development. Its crucial roles in cardiovascular development have been elucidated …

2015年10月8日 · Here we report that transcription of Isl1, a major gene necessary for motor neuron identity, is controlled by two enhancers, CREST1 (E1) and CREST2 (E2) that allow …

2023年3月10日 · We unravel the molecular mode of action of ISL1 in controlling α cell fate and the formation of functional ß cells in the pancreas.

Full gene name according to HGNC. Official gene symbol, which is typically a short form of the gene name, according to HGNC. Assigned HPA protein class (es) for the encoded protein (s). …

Using two independent transgenic and gene-targeting approaches in human embryonic stem cell lines, we show that purified ISL11 primordial progenitors are capable of self-renewal and …

2018年1月16日 · Loss and gain-of-function investigation uncovers a regulatory network controlling human heart chamber specification in which the cardiac precursor gene ISL1 accelerates …

ISL1, a transcription factor highly expressed in cardiac progenitor cells, has been reported to contribute to enhanced vascularization and reduced myocardial brosis after fi...

2017年6月17日 · In order to elucidate the role of ISL1 in breast cancer, we performed quantitative real-time polymerase chain reaction and Western blotting analysis, and we found that ISL1 …