2024年12月25日 · IGFBP2 (Insulin Like Growth Factor Binding Protein 2) is a Protein Coding gene. Diseases associated with IGFBP2 include Insulin-Like Growth Factor I and Ovarian …

在RA患者的滑液中，与正常人或骨关节炎患者相比，IGFBP2、IGFBP3和IGFBP4的水平明显升高。 在系统性红斑狼疮中，IGFBP2、IGFBP4和IGFBP6被基于阵列的蛋白质组学筛选发现为狼 …

IGFBP2是循环中第二个丰富的IGFBP，存在于许多脊椎动物的其他生物流体和组织中。 在空腹、低氧血症或创伤后的情况下血清IGFBP2水平会升高，提示IGFBP2表达的复杂调节。

2020年1月10日 · Growing evidence indicates that aberrant expression of IGFBP2 in cancer acts as a hub of an oncogenic network, integrating multiple cancer signaling pathways and serving …

IGFBP2 expression is closely linked to genes in the integrin and integrin-linked kinase pathways. IGFBP2 activates integrin beta1 and downstream invasion pathways, requires ILK to induce …

Insulin-like growth factor-binding protein 2 is a protein that in humans is encoded by the IGFBP2 gene. [5]

胰岛素样生长因子结合蛋白 2： 由该基因编码的蛋白质是结合胰岛素样生长因子 I 和 II (IGF-I 和 IGF-II) 的六种相似蛋白质之一。编码的蛋白质可以分泌到血流中，在那里它以高亲和力结合 …

The versatility of IGFBP2, as a secreted protein in cancer cells or a cytoplasmic signaling effector, has been extensively investigated in many malignant cancers. Over the last few decades, …

Here, we review and discuss the molecular structure of IGFBP2 as the first element of regulating the expression of IGFBP2. We highlight an update of the association between low serum …

2015年4月20日 · Here we present evidence that both exogenous IGFBP2 treatment and cellular IGFBP2 overexpression lead to aberrant activation of epidermal growth factor receptor …