HLA Alleles Assigned as of December 2024. There are currently 41,003 HLA and related alleles described by the HLA nomenclature and included in the IPD-IMGT/HLA Database.

The IMGT/HLA Database provides a specialist database for sequences of the human major histocompatibility complex (HLA) and includes the official sequences for the WHO Nomenclature Committee For Factors

HLA region of Chromosome 6. The human leukocyte antigen (HLA) system is a complex of genes on chromosome 6 in humans that encode cell-surface proteins responsible for regulation of the immune system. [1] The HLA system is also known as the human version of the major histocompatibility complex (MHC) found in many animals. [2]

The standardisation of HLA antigenic specifications has been controlled by the exchange of typing reagents and cells in the International Histocompatibility Workshops. How an allele is named HLA Nomenclature Reports

2021年7月1日 · Two websites provide a curated database of the sequences of over 26,000 HLA alleles and a reference site for the current nomenclature. This review covers the major steps in the development of the HLA nomenclature as well as the efforts of other groups to extend its usefulness for research and clinical applications. 1. Introduction.

2021年8月11日 · HLA为前缀，A表示基因，使用星号*与4个数字区域进行分割。 被冒号“：”分隔的四个数字区域分别标示以下内容： 一些特殊标记： 表示肽链结合区（HLA class I：exon2 和3，HLA class II ：exon2）的不确定性时，氨基酸序列（P），或是碱基序列（G）一致的等位基因，在末尾添加P或G表示。

HLA（人类白细胞抗原）命名规则是一个复杂的系统，用于唯一标识和区分人类免疫系统中的HLA分子。 这个命名系统由世界卫生组织（WHO）的HLA命名委员会维护，并且定期更新以反映新的科学发现。 以下是HLA命名规则的关键要素和一些示例。 1. 基本结构： HLA等位基因名称由一系列数字和（或）字母组成，用冒号分隔。 这些数字和字母代表不同的分子特征和遗传信息。 2. 数字组： - 第一组数字表示等位基因的类型，通常与血清学定义的抗原相关。 - 第二组数字表 …

IPD-IMGT/HLA数据库是一个专门提供人类主要组织相容性复合体 (MHC),包括WHO序列命名法委员会命名的HLA系统等位基因信息。 IPD-IMGT/HLA数据库是国际免疫遗传学项目 (IMGT)的一部分。 HLA的命名. 按照世界卫生组织HLA系统命名委员会2010年公布的等位基因命名原则，一个完整的HLA等位基因由8个数字和1个字母组成（Subtype也可能3位）。

2019年9月20日 · Each HLA allele name has a unique number corresponding to up to four sets of digits separated by colons. The length of the allele designation is dependent on the sequence of the allele and that of its nearest relative.

2024年10月22日 · In current clinical practice, the presence of allo-antibodies is assessed using Luminex-based solid phase single antigen bead (SAB) assays for transplantation. Recently, novel antigens were proposed for HLA molecules with DEP patterns that do not match any serologically defined antigens recognised by the WHO Nomenclature Committee.