Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 is a protein that in humans is encoded by the HCN4 gene. [5] [6] [7] [8] There are four HCN channels. HCN4 is …

2024年12月25日 · HCN4 (Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 4) is a Protein Coding gene. Diseases associated with HCN4 include Sick Sinus …

Hyperpolarization-activated cyclic nucleotide–gated (HCN) channels are integral membrane proteins that serve as nonselective voltage-gated cation channels in the plasma membranes of …

The HCN4 gene provides instructions for making a channel that transports positively charged atoms (ions) into heart muscle cells. This channel is located primarily in the sino-atrial (SA) …

HCN4 mutations confer diverse phenotypes, characterized by the previously described bradycardia, sick sinus syndrome, LVNC, mood and anxiety disorders, and susceptibility to VF …

2025年2月8日 · A novel mutation is found in HCN4 gene causing symptoms of sinus bradycardia in unrelated male Moroccan Jews. These findings suggest HCN4 as a genetic susceptibility …

2025年2月21日 · Hyperpolarization-activated cyclic nucleotide-gated channel 4 (HCN4) drives the funny current in cardiac pacemaker regions. Its involvement in sinoatrial node pacemaker …

The HCN4 gene encodes a member of the hyperpolarization-activated cyclic nucleotide-gated ion channel family, which are expressed at the cell membrane and contribute to the resting …

2024年9月19日 · HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 Gene ID: 10021, updated on 8-Feb-2025 Gene type: protein coding Also known as: SSS2; …

HCN4 is a gene responsible for encoding channels that generate the funny current (I f ) crucial for the automaticity of the sinoatrial node in the heart. AI generated definition based on: Cardiac …