2024年12月25日 · GANAB (Glucosidase II Alpha Subunit) is a Protein Coding gene. Diseases associated with GANAB include Polycystic Kidney Disease 3 With Or Without Polycystic Liver …

Neutral alpha-glucosidase AB is an enzyme that in humans is encoded by the GANAB gene. [5] [6] [7]

2022年7月25日 · The elevated expression of GANAB is a novel indicator of poorer prognosis of UC. Our data suggests that GANAB is not only a new and promising prognostic biomarker for …

2018年2月19日 · Human tissues contain 2 isozymes of neutral alpha-glucosidase designated AB (GANAB) and C (GANC; 104180). Initially distinguished on the basis of differences in …

Whole-exome sequencing of six GUR ADPKD-affected families identified one with a missense mutation in GANAB, encoding glucosidase II subunit α (GIIα). Because PRKCSH encodes …

2025年2月9日 · Mutations in GANAB gene is associated with Autosomal-Dominant Polycystic Kidney and Liver Disease. The high frequency of glucosidase II overexpression, which to the …

2016年6月2日 · Whole-exome sequencing of six GUR ADPKD-affected families identified one with a missense mutation in GANAB, encoding glucosidase II subunit α (GIIα). Because …

2020年10月23日 · Polycystic liver disease (PLD) is an inherited disorder characterized by numerous cysts in the liver. Autosomal dominant polycystic kidney and liver disease (ADPKD …

2020年10月23日 · GANAB encodes the α-subunit of glucosidase II (GIIα). Here, we report the identification of novel GANAB variants in an international cohort of patients with the primary …

GANAB and other GH31 neutral α-glycosidase C (GANC) are key enzymes in glycogen metabolism that hydrolyze terminal nonreducing 1,4-linked alpha-d-glucose residues from …