Growth/differentiation factor 15 is a protein that in humans is encoded by the GDF15 gene. GDF15 was first identified as Macrophage inhibitory cytokine-1 or MIC-1. [5] It is a protein belonging to the transforming growth factor beta superfamily.

2021年8月11日 · GDF15 reduces the intake of high-fat diets in animal models through binding to glial cell-derived neurotrophic factor family receptor alpha-like (GFRAL) and the recruitment of the receptor...

Growth differentiation factor 15 (GDF15) enzyme-linked immunosorbent assay is a quantitative sandwich enzyme immunoassay technique. Specimen is incubated in wells that have been coated with anti-GDF15 antibody.

Growth/differentiation factor-15 (GDF-15), also named macrophage inhibitory cytokine-1, is a divergent member of the transforming growth factor β superfamily. While physiological expression is barely detectable in most somatic tissues in humans, GDF-15 is abundant in placenta.

2024年12月11日 · Recently, growth differentiation factor 15 (GDF-15), a cytokine that is abundantly produced by many cancer types, was shown to interfere with antitumour immune response. In preclinical cancer...

Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is ...

Growth differentiation factor 15 is a cytokine that is widely used as a biomarker for the severity of diverse disease states. It also has been shown to play a protective role after tissue injury and to promote a positive energy balance during obesity and diabetes.

2024年12月25日 · GDF15 (Growth Differentiation Factor 15) is a Protein Coding gene. Diseases associated with GDF15 include Hyperemesis Gravidarum and Cardiac Rupture. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and GPCR Pathway.

2 天之前 · The cytokine GDF-15 is a member of the TGF-β protein superfamily, whose expression and secretion are induced in response to diverse stress conditions, including sustained overfeeding and ...

Growth differentiation factor-15 (GDF-15) is a stress-responsive, transforming growth factor beta-cytokine involved in inflammatory and apoptotic pathways of tissue injury.