2024年12月25日 · FABP7 (Fatty Acid Binding Protein 7) is a Protein Coding gene. Diseases associated with FABP7 include Autism Spectrum Disorder and High Grade Glioma . Among its related pathways are Triglyceride metabolism and Signaling by NOTCH3 .

Fatty acid binding protein 7 (FABP7) expressed by astrocytes in developing and mature brains is involved in uptake and transportation of fatty acids, signal transduction, and gene transcription. Fabp7 knockout (Fabp7 KO) mice show behavioral phenotypes reminiscent of human neuropsychiatric disorders …

FABP7 is almost exclusively expressed in neurospheres and not in the adherent cells, derived from the same glioblastoma tumor. A fatty acid-binding protein 7/RXRbeta pathway enhances survival and proliferation in triple-negative breast cancer.

2023年9月9日 · Fatty acid binding protein 7 (FABP7) belongs to a family of conserved proteins that regulate lipid metabolism, energy homeostasis, and inflammation. FABP7 expression is largely restricted to astrocytes and radial glia-like cells in the adult central nervous system.

2023年12月6日 · Fatty acid-binding protein 7 (FABP7) is vital for uptake and trafficking of fatty acids in the nervous system. To investigate the involvement of FABP7 in noise-induced hearing loss (NIHL)...

2021年5月2日 · We showed that FABP7 was co-localized and formed a complex with Syn in Syn-transfected U251 human glioblastoma cells, and treatment with arachidonic acid (100 M) significantly promoted...

We focus on brain FABP (FABP7), which demonstrates localization to the cytoplasm and nucleus, influencing transcription and fatty acid metabolism. We use a combined biophysical-computational approach to elucidate the interaction between FABP7 and model membranes.

2024年11月27日 · Title: Nuclear FABP7 regulates cell proliferation of wild-type IDH1 glioma through caveolae formation. Plasma fatty acid-binding protein 7 concentration correlates with depression/anxiety, cognition, and positive symptom in patients with schizophrenia.

2025年2月8日 · the synchronized, global cycling pattern of Fabp7 expression is unique and implicates glial cells in the response or modulation of activity and/or circadian rhythms. FABP7 plays a novel and crucial role, linking the NMDA, neurodevelopmental, and glial theories of schizophrenia pathology.

In the spinal cord of symptomatic mutant hSOD1-expressing mice, FABP7 is up-regulated in gray matter astrocytes. Using a co-culture model, we examined the effect of increased FABP7 expression in astrocyte-motor neuron interaction.