2024年12月25日 · ETV1 (ETS Variant Transcription Factor 1) is a Protein Coding gene. Diseases associated with ETV1 include Skeletal Ewing Sarcoma and Soft Tissue Sarcoma. Among its …

2016年10月24日 · ETV1 is a NRG1-responsive factor that is highly expressed in PAM and VCS myocytes, where it establishes the fast conduction phenotype through enrichment of Nkx2-5, …

ETV1 and COP1 are a pair of independent predictors of prognosis for triple-negative breast cancer. ETV1 overexpression is associated with prostate cancer aggressiveness. Results …

2010年10月3日 · We propose that GIST arises from ICCs with high levels of endogenous ETV1 expression that, when coupled with an activating KIT mutation, drives an oncogenic ETS …

Here, we review evidence for a role of ETV1, 4 and 5 as oncoproteins and describe modes of their action. Modulation of their activation or interaction with cofactors as well as inhibiting crucial …

2019年6月3日 · First, we discovered that ETV1 forms complexes with SMAD4. Second, SMAD2, SMAD3 and SMAD4 overexpression impaired ETV1’s ability to stimulate gene transcription.

2018年7月2日 · Cardiomyocyte-specific deletion of ETV1 results in cardiac conduction abnormalities, decreased expression of rapid conduction genes (Nkx2–5, Gja5, and Scn5a), …

Cardiomyocyte-specific deletion of ETV1 results in cardiac conduction abnormalities, decreased expression of rapid conduction genes (Nkx2–5, Gja5, and Scn5a), HPS hypoplasia, and …

2015年12月8日 · ETV1, which is mutated in prostate cancer more often, was degraded after being ubiquitinated by COP1. Truncated ETV1 encoded by prostate cancer translocation …

2024年11月2日 · Transcription factor ETV1-induced lncRNA MAFG-AS1 promotes migration, invasion, and epithelial-mesenchymal transition of pancreatic cancer cells by recruiting …