CD5 includes a scavenger receptor cysteine-rich protein domain. T cells express higher levels of CD5 than B cells. CD5 is upregulated on T cells upon strong activation. In the thymus, there is …

2025年1月30日 · CD5 is typically expressed in chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL), thereby distinguishing these disorders from other small chronic B cell …

2023年5月25日 · It had been clear, that the antiquated T cell marker CD5 is important for T cell receptor signaling fine tuning and for protection from activation-induced cell death. 2 …

2024年12月24日 · CD5 (CD5 Molecule) is a Protein Coding gene. Diseases associated with CD5 include Thymic Carcinoma and Prolymphocytic Leukemia. Among its related pathways are …

CD5 is a molecule involved in signal transduction through tyrosine phosphorylation of intracellular proteins. It plays a role in modulating signaling via antigen-specific receptor complexes in T …

The study of CD5 deficient mice allowed to position CD5 not only as an activation marker but also as an active player of the TCR signaling pathway . Indeed, absence of CD5 enhanced …

CD5 is an important physiological regulator of T-cell immune responses. The regulation of CD5 corresponds to a key event in the maintenance of immune homeostasis and tolerance.

CD5 is a specialized type of protein normally found on the surface of immune cells where it is involved in modulating signal transduction pathways. It plays a significant role in regulating …

CD5 is a member of the scavenger receptor cysteine-rich (SRCR) superfamily and has a cytoplasmic tail with no enzymatic activity but with a motif that serves as docking sites for …

CD5 is a well established negative regulator of TCR and BCR signalling. In the last years, great advances have been made in understanding the molecular mechanisms behind this regulatory …