Learn how to activate T cells with functional antibodies CD3 and CD28 with this detailed protocol.

We want to make it easier to activate and expand human T cells while still maintaining a high viability of these cells. That's why we developed ImmunoCult™ Human CD3/CD28 T Cell …

2014年1月27日 · This has been developed primarily in the context of cell interaction with extracellular matrix through integrins, but recent studies showed that T cells exhibit …

T Cell TransAct™ consists of a colloidal polymeric nanomatrix conjugated to humanized CD3 and CD28 agonists providing primary and co-stimulatory signals for an optimized and efficient T …

We engineered two recombinant cross-interacting Bs-Abs (CriBs-Abs) by incorporating a peptide tag and its cognate single-chain variable fragment (scFv), respectively, into a pair of (tumor × …

CD28 is critical for regulatory T cell survival and the maintenance of immune homeostasis. We outline the roles that CD28 and its family members play in human disease and we review the …

Analogous to using similar or identical CD3-binding domains in multiple CD3 TCEs, the same monovalent CD28-binding domain in XmAb808 can be readily coupled with binding domains …

2020年1月8日 · Here, we introduce a class of bispecific antibodies that mimic signal 2 by bridging TSA to the costimulatory CD28 receptor on T cells. We term these TSAxCD28 bispecifics and …

The CD28 antibody recognizes the human CD28 antigen, a type I transmembrane protein, which is highly expressed on CD3 + thymocytes, most peripheral thymocytes and plasma cells. …

2025年2月17日 · The CD64-CR is the major driver of the proliferation, expansion, and persistence of Fcγ-CR/CD28/CD3ζ T cells. (A) CD3-activated human T cells were transduced with CD16 …