
Pathology Outlines - Stains & CD markers
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Pathology Outlines - CD20
2021年9月20日 · Rituximab is a chimeric murine / human anti-CD20 antibody used to treat B cell lymphomas; treatment may cause selection of CD20 negative (but CD79a positive) tumor subclones (Am J Surg Pathol 2005;29:1399, Ann Hematol 2020;99:2141)
Pathology Outlines - CD5
2025年1月30日 · Absence of CD5 expression may be associated with superior overall survival and more favorable progression free survival in mantle cell lymphoma (Am J Surg Pathol 2019;43:1052)
Pathology Outlines - Hemorrhoids
Hemorrhoids are normal vascular structures present as cushions that help to maintain continence; typically defined as symptomatic enlargement and distal displacement of the normal anal cushions
Pathology Outlines - BCL6
2023年8月3日 · A lymph node biopsy morphologically demonstrates involvement by a large cell lymphoma. The neoplastic cells stain positive for CD20, BCL6, BCL2, MUM1 and MYC and negative for CD3, CD10, CD30 and CD138.
Pathology Outlines - DLBCL, NOS
2022年5月24日 · Cell of origin subtype prediction by IHC using the Hans algorithm (positivity defined as staining in ≥ 30% of cells) (Blood 2004;103:275):
Pathology Outlines - Renal cell carcinoma (RCC)
2022年2月16日 · Anti renal cell carcinoma (RCC) antibodies detect a 200 kD glycoprotein (gp200), which is a surface membrane molecule located on the brush border of proximal renal tubules (Am J Surg Pathol 2001;25:1485)
Pathology Outlines - Endometrial hyperplasia
2024年7月2日 · Endometrial hyperplasia without atypia (Semin Diagn Pathol 2010;27:199) Architecture Closely packed glands such that gland to stroma ratio is > 3:1 but stroma is still present between glandular basement membranes (however minimal)
Pathology Outlines - Benign prostatic hyperplasia
2021年7月12日 · Benign nodular enlargement of the prostate gland . Watchful waiting for patients with mild symptoms or moderate to severe symptoms with minimal impairment in quality of life (Annu Rev Med 2016;67:137)
Pathology Outlines - Nonalcoholic fatty liver disease / …
2020年7月1日 · Liver & intrahepatic bile ducts nontumor - nonalcoholic fatty liver disease (NAFLD) / nonalcoholic steatohepatitis (NASH)