2024年12月24日 · CCND1 (Cyclin D1) is a Protein Coding gene. Diseases associated with CCND1 include Myeloma, Multiple and Von Hippel-Lindau Syndrome. Among its related …

2016年5月16日 · Cyclin D1 (Ccnd1) together with its binding partner Cdk4 act as a transcriptional regulator to control cell proliferation and migration, and abnormal Ccnd1·Cdk4 expression …

2025年2月9日 · CCND1 mutations increase protein stability and promote ibrutinib resistance in mantle cell lymphoma. Mohanty A, et al. Oncotarget, 2016 Nov 8. PMID 27713153, Free PMC …

2025年1月5日 · Clinical resource with information about CCND1, A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and …

This systematic review and meta-analysis of 41 studies and 3451 patients, shows CCND1 /cyclin D1 upregulation as a common oncogenic alteration in cutaneous, mucous, and uveal …

2025年2月9日 · CCND1 alternate transcripts encode proteins with differing functions: CCND1 (tra) encodes protein involved in regulating mitogen responsive, anchorage-dependent …

Cyclin D1 (CCND1) is a core cell cycle regulator and is frequently overexpressed in human cancers, often via amplification, translocation or post-transcription regulation. Accumulating …

2020年8月10日 · These findings indicate that CCND1 amplification may be a key point related to immunosuppression in TME and multiple malignancy hallmarks, and it hinders not only the …

CCND1 was one of the HUB genes that our RT-PCR studies confirmed to be overexpressed in IDCM patients. CCND1 is a proto-oncogene that manages progression via the G1-S phase of …

2024年11月26日 · CCND1 amplification is a recurring event in breast cancer, occurring most frequently in luminal B-like and HER2-amplified subtypes. A trend toward less favorable …