Aflatoxin B 1 is considered the most toxic aflatoxin and it is highly implicated in hepatocellular carcinoma (HCC) in humans. [9] . In animals, aflatoxin B 1 has also been shown to be …

The suspect human hepatocarcinogen aflatoxin B1 (AFB1) is a well-known potent initiator of hepatic tumors in rainbow trout (Oncorhynchus mykiss). Both hepatocellular carcinomas and …

2023年2月19日 · AFB1 is believed to be the most potent among all aflatoxins. Aflatoxin M1 (AFM1) is found in the fermentation broth of A. parasiticus, but it and aflatoxin M2 are also …

In the case of aflatoxin B1 (AFB1), the best studied aflatoxin, AFB1-exo 8,9-epoxide, which is formed as the first step of AFB1 metabolism by microsomal cytochrome enzyme (CYP450) …

Aflatoxin B1 (AFB1) is a fungal metabolite found in animal feeds and human foods. It is one of the most toxic and carcinogenic of aflatoxins and is classified as a Group 1 carcinogen. Dietary …

AFB1 is a lipid-soluble agent that is synthesized optimally at 25 °C and is a derivative of difuranoxano-naphtho-ketone consisting of a difuran ring and a coumarin ring, is carcinogenic, …

This review focuses on the metabolism of AFB1, including epoxidation and DNA adduction, as it concerns the initiation of cancer and the underlying mechanisms. The link between AFB1 …

2019年2月1日 · Aflatoxin B1 (AFB1) is the most potent of these compounds and has been well-characterized to lead to the development of hepatocellular carcinoma (HCC) in humans and …

AFB1 is the most carcinogenic of AF. AFB1 contamination of agricultural commodities poses a considerable risk to human and livestock health and high economic losses occur in the country …

2024年11月11日 · Aflatoxin B1 (AFB1) is a mycotoxin that widely found in the environment and mouldy foods. AFB1 initially targets the intestine, and AFB1-induced intestinal injury cannot be …