The 5-HT 3 receptor belongs to the Cys-loop superfamily of ligand-gated ion channels (LGICs) and therefore differs structurally and functionally from all other 5-HT receptors (5-hydroxytryptamine, or serotonin receptors) which are G protein-coupled receptors.

血清素（英语：Serotonin，全称血清张力素，又称5-羟色胺和血清胺，简称为5-HT）为单胺型神经递质，由 色氨酸 经色氨酸羟化酶转化为5-羟色氨酸，再经5-羟色氨酸脱羧酶在中枢神经元及动物（包含人类）消化道之 肠嗜铬细胞 中合成。5-羟色胺主要存在于动物 ...

5-ht3 受体阻断药，是指药物通过与外周胃肠嗜铬细胞和中枢的5-ht受体结合，抑制5-ht的释放及阻断向呕吐中枢的冲动传入，具有抑制呕吐发生的一类药物。

5-HT3 receptor antagonists (also called serotonin receptor antagonists or serotonin blockers) are a class of medicines that are used for the prevention and treatment of nausea and vomiting, particularly that caused by chemotherapy, radiation therapy, or postoperatively. 5-HT3 is an abbreviation for serotonin that may also be written as 5 ...

2024年1月15日 · 5-羟色胺3受体（5-hydroxytryptamine type 3 receptor，5-HT 3 R）是5-羟色胺受体家族中唯一的一类配体门控离子通道，通过对Na + 、K + 、Ca 2+ 等离子的高通透性以及继发性电压门控Ca 2+ 离子通道的激活从而诱发神经元兴奋性的快速上调或轴突末梢的神经递质释放。

5-HT 3 receptors are ligand-gated ion channels (LGIC) and therefore differ from all other 5-HT (serotonin) receptors whose actions are mediated via G proteins. Their structure and function has placed them in the Cys-loop family of ligand-gated ion channels.

5-羟色胺受体，也被称为血清素受体或5-ht受体，是一群于中枢神经系统中央处和末梢神经系统周边出现的g蛋白偶联受体及配体门控离子通道。 它们同时调节兴奋性和抑制性神经传导物质的传递。

Serotonin type 3 (5-HT(3)) receptors are pentameric ion channels belonging to the superfamily of Cys-loop receptors. Receptor activation either leads to fast excitatory responses or modulation of neurotransmitter release depending on their neuronal localisation. 5-HT(3) receptors are …

2024年4月29日 · 5-ht受体是一群位于中枢神经系统和末梢神经系统周边的g蛋白偶联受体及配体门控离子通道。它们同时调节兴奋性和抑制性神经传导物质的传递。5-ht受体可分为七个亚型：5-ht1、5-ht2、5-ht3、5-ht4、5-ht5、5-ht6与5-ht7。

5-hydroxytryptamine receptor subtype 3 (5-HT 3 R) is a pentameric ligand-gated ion channel (pLGIC) involved in neuronal signaling. It is best known for its prominent role in gut-CNS signaling though there is growing interest in its other functions, particularly in modulating non-serotonergic synaptic activity.