The application of a murine cancer cell line, such as 4T1, in a mouse model is of great value for preclinical TNBC studies. The 4T1 cell line is widely used as a syngeneic model for human …

4T1 is a 6-thioguanine resistant cell line selected from the 410.4 tumor without mutagen treatment. When injected into BALB/c mice, 4T1 spontaneously produces highly metastatic …

Surgically-Induced Multi-organ Metastasis in an Orthotopic Syngeneic Imageable Model of 4T1 Murine Breast Cancer.

4T1 is a breast tumour cell line originating from a mammary tumour that spontaneously arose in mouse BALB/c strain. These highly invasive and tumorigenic cells closely mimic human breast …

The 4T1 cell line is considered an animal model for stage IV human breast cancer, as it is able to spontaneously metastasize in both post-operative and non-surgical models (CLS=300300). …

4T1-Luc2 cells are a luciferase-expressing cell line derived from parental line CRL-2539 by transduction with lentiviral vector encoding firefly luciferase gene (luc2) under control of EF-1 …

2020年7月23日 · The 4T1 murine mammary cancer cell line is one of the most widely used breast cancer models. Here, we present an integrated map of the genome, transcriptome, and …

The well-characterized 4T1 series of cell lines 38 includes five isogenic tumorigenic lines (67NR, 168FARN, 4TO7, 66cl4, and 4T1) that originated from one spontaneous tumor in a …

2024年9月1日 · To investigate how E-cadherin regulates metastasis, we examined the highly metastatic, E-cadherin-positive murine 4T1 breast cancer model, together with the less …

2008年8月9日 · The 4T1 mouse mammary tumor cell line is one of only a few breast cancer models with the capacity to metastasize efficiently to sites affected in human breast cancer. …