2024年12月25日 · TCL1A (TCL1 Family AKT Coactivator A) is a Protein Coding gene. Diseases associated with TCL1A include Leukemia and Precursor T-Cell Acute Lymphoblastic …

T-cell leukemia/lymphoma protein 1A is a protein that in humans is encoded by the TCL1A gene. [5] [6] [7]

2023年3月23日 · Downregulated CDC20 in CLL cells resembles the aneuploidy phenotype and is associated with more aggressive disease and cellular features. Proposed integrative model of …

Identification of T-cell leukemia and lymphoma protein overexpression in neoplasms. For the initial technical component only immunohistochemical (IHC) stain performed, the appropriate bill …

2021年6月1日 · TCL1A has first been identified as an oncogene, overexpression of which is associated to the development of T and B cell cancer. TCL1A acts as a coactivator of the …

Distinct nuclear and cytoplasmic expression in subsets of immune cells in the mantle zone. Main subcellular location based on data generated in the subcellular section of the Human Protein …

2018年8月12日 · Almost 30 years ago, Carlo Croce's group discovered the T-Cell Leukemia/Lymphoma 1A oncogene (TCL1A or TCL1). TCL1 protein is normally expressed in …

TCL1A - Explore an overview of TCL1A, with a histogram displaying coding mutations, full tabulated details of all associated variants, tissue distribution and any drug resistance data.

T-cell leukemia/lymphoma 1A (TCL1A; also known as TCL1) is a gene that encodes a protein that functions as a coactivator of AKT - a cell survival kinase. The protein is also important for the …

To determine how TCL1 proteins cause cancer, it is crucially important that we determine the mechanisms of TCL1-family gene regulation and dysregulation, understand potential AKT …