Abundant and functionally important types of non-coding RNAs include transfer RNAs (tRNAs) and ribosomal RNAs (rRNAs), as well as small RNAs such as microRNAs, siRNAs, piRNAs, snoRNAs, snRNAs, exRNAs, scaRNAs and the long ncRNAs such as Xist and HOTAIR.

2024年11月14日 · Here, we present our current understanding of the most extensively studied ncRNAs—microRNAs (miRNAs) and long non-coding RNAs (lncRNAs)—that have contributed to the modern regulatory RNA field in eukaryotes.

snRNAs comprise a small group of highly abundant, non-polyadenylated, non-coding transcripts that function in the nucleoplasm. The snRNAs can be divided into two classes on the basis of common...

During the last decade, it has become evident that small non-coding RNAs (ncRNAs) participate in widespread and essential regulatory mechanisms in most eukaryotic cells. Novel classes of small RNAs, their biogenesis pathways and cellular effects are ...

Based on their average size, regulatory ncRNAs could be further classified as small non-coding RNAs (sncRNAs) with comprising transcripts fewer than 200 nt, and lncRNAs with greater than 200 nt. The main classes of small ncRNAs are microRNA (miRNA), small interfering RNAs (siRNAs), piwi-interacting RNAs (piRNAs).

In this chapter, we will introduce several classes of short and long non-coding RNAs, describe their diverse roles in mammalian gene regulation and give examples for known modes of action. Keywords: Biogenesis; Classification; Function; Non-coding RNA; lncRNA; miRNA; piRNA; rRNA; snRNA; snoRNA; tRNA.

2022年4月12日 · Small noncoding RNAs (sncRNAs) are universally distributed in all kingdoms of life—from bacteria and archaea to various eukaryotic organisms 1, 2, 3 —and have not ceased to surprise us...

2021年10月26日 · Small non-coding RNAs are short RNA molecules and involved in many biological processes, including cell proliferation and differentiation, immune response, cell death, epigenetic regulation, metabolic control.

The small nuclear and small nucleolar RNPs are two well studied classes of ncRNPs with elaborate assembly and trafficking pathways that provide paradigms for understanding the biogenesis of other ncRNPs.

2024年8月17日 · Small non-coding RNAs (sRNAs) play important roles in regulating gene expression across all cellular organisms, including Gram-negative bacteria. Small non-coding RNAs are typically 50–500 nucleotides long and do not code for proteins.