Genetics constitute a crucial risk factor to schizophrenia. In the last decade, molecular genetic research has produced novel findings, infusing optimism about discovering the biological roots …

2023年10月18日 · Genetic findings have revealed the nature of schizophrenia’s close relationship to other conditions, particularly BD and childhood NDDs and provided an explanation for how …

2016年1月27日 · The site in Chromosome 6 harboring the gene C4 towers far above other risk-associated areas on schizophrenia’s genomic “skyline,” marking its strongest known genetic …

2009年6月13日 · Three international research teams have detected many tiny and common gene variations that together could account for at least one-third of the genetic risk for …

Schizophrenia is a common and serious psychiatric illness with strong evidence for genetic causation, but no specific loci yet identified. Chromosomal abnormalities associated with …

2024年1月23日 · Most people who have schizophrenia first develop symptoms between the ages of 16 and 30. Researchers don’t know exactly what causes the illness, or why it emerges at …

The Epsin 4 gene on chromosome 5q, which encodes the clathrin-associated protein enthoprotin, is involved in the genetic susceptibility to schizophrenia. Am J Hum Genet. 2005;76:902–907. …

2024年7月19日 · In this Review, we describe what we now know about the genetics of schizophrenia and consider the neurobiological implications of this information.

2024年10月10日 · Genomic patterns that underlie brain mosaicism hold potential to dissect the complex genetic architecture of schizophrenia. Such mutational signatures may further help to …

2013年8月12日 · People with schizophrenia have a high number of spontaneous mutations in genes that form a network in the front region of the brain. The findings reveal new clues about …