R-spondin-1 is a secreted protein that in humans is encoded by the RSPO1 gene, found on chromosome 1. [5] In humans, it interacts with WNT4 in the process of female sex …

2024年12月25日 · RSPO1 (R-Spondin 1) is a Protein Coding gene. Diseases associated with RSPO1 include Palmoplantar Hyperkeratosis With Squamous Cell Carcinoma Of Skin And …

RSPO1 (locus: 1p34.3) encodes a secreted activator protein essential for female sex determination. It regulates ovarian development by upregulating the WNT/β-catenin pathway …

2021年10月18日 · R-spondin (RSPO) proteins constitute a family of four secreted glycoproteins (RSPO1–4) that have appeared as multipotent signaling ligands. The best-known molecular …

2025年1月4日 · Title: Serum R-Spondin 1 Is a New Surrogate Marker for Obesity and Insulin Resistance. R-spondin1/Wnt activated Ascl2 expression dose-dependently in the CD133 …

2025年2月8日 · RSPO1 regulates Wnt signaling by inhibiting internalization of LRP6. Human R-spondin1 (RSPO1) is the gene disrupted in a recessive syndrome characterized by XX sex …

R-spondin-1 (Rspo1) is an intestinal growth factor known to exert its effects through activation of the canonical Wnt (cWnt) signaling pathway and subsequent expression of cWnt target genes. …

Here, we generated a recombinant human RSPO1 (rhRSPO1) using the HEK293 cell line, obtaining a purified, characterized and biologically active protein product to be used in Cell …

2024年1月29日 · Clinical resource with information about RSPO1, Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error., …

R-Spondin 1 (RSPO1, also known as Roof plate-specific Spondin 1) is a 27 kDa secreted protein that belongs to the R-Spondin family. It shares approximately 40% amino acid identity with …