A plexin is a protein which acts as a receptor for semaphorin family signaling proteins. [1] [2] [3] It is classically known for its expression on the surface of axon growth cones and involvement in …

2014年8月1日 · Several semaphorins and plexins are critically involved in tumour growth and metastasis by controlling tumour development and progression via the formation of autocrine …

Plexin-A4 is a protein that in humans is encoded by the PLXNA4 gene. [5] Plexin A4 binds to neuropilin 1 (Nrp1) and neuropilin 2 (Nrp2) and transduces signals from Sema3A, Sema6A, …

A Plexin is a type of transmembrane protein found in cells, characterized by the presence of a Sema domain at their N-terminus, a cysteine-rich motif in their extracellular region, and a …

Class A plexins (PlxnAs) act as semaphorin receptors and control diverse aspects of nervous system development and plasticity, ranging from axon guidance and neuron migration to …

2025年2月1日 · Plexins are a family of transmembrane receptors known for their diverse roles in neural development, axon guidance, neuronal migration, synaptogenesis, and circuit …

2019年2月13日 · Remarkably, we detected plexins and semaphorins in unicellular choanoflagellates, indicating their evolutionary origin in a common ancestor of …