Omeprazole is a selective and irreversible proton pump inhibitor. Omeprazole suppresses gastric acid secretion by specific inhibition of the hydrogen-potassium adenosinetriphosphatase (H+, K+-ATPase) enzyme system found at the secretory surface of parietal cells.

Omeprazole, sold under the brand names Prilosec and Losec, among others, is a medication used in the treatment of gastroesophageal reflux disease (GERD), peptic ulcer disease, and Zollinger–Ellison syndrome. [1] . It is also used to prevent upper gastrointestinal bleeding in people who are at high risk. [1] .

[PubChem] Esomeprazole is a proton pump inhibitor that suppresses gastric acid secretion by specific inhibition of the H + /K + -ATPase in the gastric parietal cell. By acting specifically on the proton pump, Esomeprazole blocks the final step in acid production, thus reducing gastric acidity.

Omeprazole Sodium is the sodium salt form of a benzimidazole with selective and irreversible proton pump inhibitor activity.

ChemSpider record containing structure, synonyms, properties, vendors and database links for Omeprazole, 73590-58-6, Miol, SUBDBMMJDZJVOS-UHFFFAOYSA-N

2012年6月5日 · The 3D chemical structure image of omeprazole is based on the ball-and-stick model which displays both the three-dimensional position of the atoms and the bonds between them. The radius of the spheres is therefore smaller than the rod lengths in order to provide a clearer view of the atoms and bonds throughout the chemical structure model of ...

2015年12月31日 · Omeprazole is a proton pump inhibitor used to treat GERD associated conditions such as heartburn and gastric acid hypersecretion, and to promote healing of tissue damage and ulcers caused by gastric acid and H. pylori infection.

2020年10月22日 · The drug information on OMEPRAZOLE include structure, IUPAC, physiochemical properties, synthesis, SAR, MOA, therapeutic uses, side effects and MCQs for GPAT and other exam preparations.

2015年4月7日 · Omeprazole, 5 (6)-methoxy-2- { (4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl}-1H-benz – imidazole [1 (2)], is an important ulcer drug,1 that has been classified amongst the blockbuster drugs.2 This compound …

In this study we characterize the structural and biochemical/ catalytic properties of the A82F, F87V, and F87V/A82F mutants of BM3, demonstrating a novel activity in oxidation of the widely used...