
October 4 - Wikipedia
October 4 is the 277th day of the year (278th in leap years) in the Gregorian calendar; 88 days remain until the end of the year.
Oct4--胚胎干细胞多能性的看门人 - 知乎 - 知乎专栏
Oct4 (Octamer-binding transcription factor)因能与八聚体模体的DNA结合而命名,也被称为Oct3、 POU5F1 、 Oct-3/4 、Otf3或NF-A3,由 Pou5f1基因 编码,属于POU转录因子家族第Ⅴ亚家族。 Oct4是 胚胎干细胞 多能性的看门人,对于维持胚胎干细胞的多潜能性和自我更新具有极其重要的作用,也是产生 诱导多能干细胞 的必要因子。 此外,Oct4在多种肿瘤中高表达,Oct4可能参与恶性肿瘤的发生发展过程。 1. Oct4的组织特异性. 2. 什么是Oct4基因? 3. Oct4基因的调 …
Historical Events on October 4 - On This Day
Historical events for the 4th of October. See what famous, interesting and notable events happened throughout history on October 4.
Oct4 - 百度百科
Oct4 Isoform 1是转录的主要亚型之一,具有5个外显子,4个内含子,翻译的蛋白质含有一个保守的DNA结合结构域——POU结合域,它能与含八聚体基序(octamer motif)的DNA结合从而调控下游靶基因的转录。
What Happened on October 4 - On This Day
2012年10月4日 · End of the Battle of Lake Poyang; Chinese rebel forces led by Zhu Yuanzhang defeat those of his rival, Chen Youliang, in one of the largest naval battles in history with approximately 850,000 participants. Gutzon Borglum begins sculpting Mount Rushmore and works on it until 1941.
What happened on october 4 in history? - California Learning …
2025年1月4日 · From major wars to groundbreaking scientific discoveries, October 4 has seen its fair share of memorable events. In this article, we’ll explore some of the most notable occurrences that have taken place on this day. Early Events. 1260 BC: The Merneptah Stele, an ancient Egyptian artifact, was created.
Oct-4 - Wikipedia
Oct-4 (octamer-binding transcription factor 4), also known as POU5F1 (POU domain, class 5, transcription factor 1), is a protein that in humans is encoded by the POU5F1 gene. [5] Oct-4 is a homeodomain transcription factor of the POU family. It is critically involved in the self-renewal of undifferentiated embryonic stem cells. [6]
On This Day - What Happened on October 4 | Britannica
On This Day In History - October 4: anniversaries, birthdays, major events, and time capsules. This day's facts in the arts, politics, and sciences.
Oct4靶点介绍及实验小贴士| Abcam中文官网
Oct4 是一种在未分化的胚胎干细胞和胚胎生殖细胞中高表达的转录因子。 Oct4与SOX2 或 SOX15 在DNA 上形成三聚体复合物,并调控许多参与胚胎发育的基因的表达,例如YES1、FGF4、UTF1和ZFP206。 对早期胚胎发生和胚胎干细胞多能性至关重要。 Oct4 可以作为胚胎干细胞标志物。 在未分化的胚胎干细胞中高表达,在胚状体(EB)形成后表达逐渐下降。 在发育中的大脑表达,在皮层、嗅球、海马和小脑的特定细胞层中高表达。 在成人组织中低表达。 Oct4表达具 …
Oct4——胚胎干细胞多能性的守门人 研究热点|生物学前沿技术|行 …
2023年11月1日 · Oct4是胚胎干细胞多能性的守门人,对于维持胚胎干细胞的多能性和自我更新起着极其重要的作用。 Oct4还对诱导多能干细胞的产生至关重要。 此外,Oct4在多种肿瘤中高度表达,这表明Oct4可能参与恶性肿瘤的发生和发展。 1. Oct4的组织特异性. 2. Oct4的组织特异性? 3. Oct4基因的调控. 4. Oct4的功能. 1. Oct4的组织特异性. Oct4在发育中的大脑中表达,高水平表达于皮层、嗅球、海马和小脑等特定细胞层。 此外,Oct4主要在胚胎干细胞、胚胎生殖细胞和 …