2024年12月25日 · MSR1 (Macrophage Scavenger Receptor 1) is a Protein Coding gene. Diseases associated with MSR1 include Barrett Esophagus and Metabolic Dysfunction-Associated Steatotic Liver Disease. Among its related pathways are Binding and Uptake of Ligands by Scavenger Receptors and Vesicle-mediated transport.

2022年10月17日 · Macrophage scavenger receptor 1 (MSR1), also named CD204, holds key inflammatory roles in multiple pathophysiologic processes. Present primarily on the surface of various types of macrophage, this receptor variably affects processes such as atherosclerosis, innate and adaptive immunity, lung and liv …

2022年10月17日 · Macrophage scavenger receptor 1 (MSR1), also named CD204, holds key inflammatory roles in multiple pathophysiologic processes. Present primarily on the surface of various types of macrophage, this receptor variably affects processes such as atherosclerosis, innate and adaptive immunity, lung and liver disease, and more recently, cancer.

Role of macrophage scavenger receptor MSR1 in the progression of non-alcoholic steatohepatitis. MSR1 characterized by chromatin accessibility mediates M2 macrophage polarization to promote gastric cancer progression. Comprehensive analysis of the prognostic and role in immune cell infiltration of MSR1 expression in lower-grade gliomas.

Msr1, also known as scavenger receptor a1 (Scara1), is a type II transmembrane glycoprotein mainly expressed by microglia in CNS [16]. Msr1 has been involved in many macrophage-associated physiological and pathological conditions such as neurodegenerative diseases [17].

Herein, we show that the macrophage scavenger receptor MSR1, an innate immune receptor, mediates lipid uptake and accumulation in Kupffer cells, resulting in liver inflammation and thereby promoting the progression of NAFLD in humans and mice.

2017年4月10日 · In this study, we identified Msr1, Marco, and Mafb as genes with key roles in the internalization of DAMPs by mononuclear phagocytes. We propose a new strategy to improve ischemic brain injury by...

2025年1月3日 · Macrophage scavenger receptor 1 (MSR1), as a key receptor in macrophages, is essential in tumor immunity. However, its mechanisms in regulating tumor progression and immunity and its prognostic value in LUSC remain unclear.

2025年2月4日 · Macrophage MSR1 promotes the formation of foamy macrophage and neuronal apoptosis after spinal cord injury. Scavenger receptor A impairs interferon response to HBV infection by limiting TRAF3 ubiquitination through recruiting OTUB1. Scavenger receptor-A is a biomarker and effector of rheumatoid arthritis.

2025年1月3日 · Macrophage scavenger receptor 1 (MSR1), as a key receptor in macrophages, is essential in tumor immunity. However, its mechanisms in regulating tumor progression and immunity and its prognostic value in LUSC remain unclear.