2022年7月26日 · MEF2C deficiency is an extremely rare genetic disorder caused by a change (mutation) in the MEF2C gene. This mutation, often a deletion, leads to the dysfunction of …

Myocyte-specific enhancer factor 2C also known as MADS box transcription enhancer factor 2, polypeptide C is a protein that in humans is encoded by the MEF2C gene. [4] [5] MEF2C is a …

2024年12月25日 · MEF2C (Myocyte Enhancer Factor 2C) is a Protein Coding gene. Diseases associated with MEF2C include Neurodevelopmental Disorder With Hypotonia, Stereotypic …

2024年12月12日 · MEF2C encodes myocyte-specific enhancer factor 2C (MEF2C), a member of the MADS family of transcription factors, which regulate hundreds of downstream gene targets …

2024年4月8日 · We identify myocyte enhancer factor 2C (MEF2C) as a master regulator of human NK cell functionality ex vivo. MEF2C-haploinsufficient patients and mice displayed …

Gene ID: 4208, updated on 8-Feb-2025. This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. …

What is MEF2C haploinsufficiency syndrome? MEF2C haploinsufficiency syndrome is a genetic condition which affects body development, in particular development of the brain. The …

MEF2C promotes precursor cell commitment towards lymphoid rather than myeloid lineages and promotes development towards monocyte rather than granulocyte fates . In B-cells, MEF2C …

4 天之前 · MEF2C, a member of the MADS box transcription enhancer factor 2 (MEF2) family, 13 is highly expressed in microglia. 14, 15 Recent studies suggested that Mef2c functioned as an …

2017年7月1日 · Myocyte enhancer factor 2C (MEF2C) is a transcription factor of MADS box family involved in the early development of several human cells including muscle (i.e., skeletal, …

What is MEF2C and why does it matter? Myocyte Enhancer Factor 2C (MEF2C) is a gene located on chromosome 5 band 14.3. The MEF2C gene encodes for a type of protein known as a …

Myocyte Enhancer Factor 2 C (MEF2C), one of the transcription factors of the MADS-BOX family, is involved in embryonic brain development, neuronal formation and differentiation, as well as …

MEF2C regulates inhibitory/excitatory (E/I) synapse density. Deficiency in fear learning, memory, various social conduct, socially-motivated ultrasonic vocalizations and reward-related …

2021年11月3日 · Overexpressing Mef2a/c in a mouse model of tauopathy improved cognition and reduced overexcitability. The results suggest that MEF2 might be a valuable target for limiting …

2008年7月8日 · We show that deletion of the MEF2C transcription factor in the CNS of mice impairs hippocampal-dependent learning and memory. Unexpectedly, these behavioral …

2022年2月22日 · Here, we show that myocyte enhancer factor 2 C (MEF2C) is essential for regulating M1 macrophage polarization in response to infection and inflammation. Global gene …

Myocyte enhancer factor 2C (MEF2C) is a transcription factor of MADS box family involved in the early development of several human cells including muscle (i.e., skeletal, cardiac, and …

Title: Aberrant ecotropic viral integration site-1 (EVI-1) and myocyte enhancer factor 2 C gene (MEF2C) in adult acute myeloid leukemia are associated with adverse t (9:22) & 11q23 …

2022年1月6日 · Myocyte Enhancer Factor 2 C (MEF2C), one of the transcription factors of the MADS-BOX family, is involved in embryonic brain development, neuronal formation and …

2021年2月10日 · Myocyte enhancer factor 2C (MEF2C) is a transcription factor that regulates heart and skeletal muscle differentiation and growth. Several protein-encoding genes were...