Long non-coding RNA - Wikipedia
Long non-coding RNAs (long ncRNAs, lncRNA) are a type of RNA, generally defined as transcripts more than 200 nucleotides that are not translated into protein. [2] This arbitrary limit distinguishes long ncRNAs from small non-coding RNAs, such as microRNAs (miRNAs), small interfering RNAs (siRNAs), Piwi-interacting RNAs (piRNAs), small nucleolar ...
Long non-coding RNAs: definitions, functions, challenges and ...
2023年1月3日 · Genes specifying long non-coding RNAs (lncRNAs) occupy a large fraction of the genomes of complex organisms. The term ‘lncRNAs’ encompasses RNA polymerase I (Pol I), Pol II and Pol III...
Long non-coding RNAs: definitions, functions, challenges and ...
The long precursor RNAs transcribed from chromosomal regions (‘genes’) before splicing and assembly of the exons into an mRNA or long non-coding RNA and before processing of the intronic RNAs into trans-acting smaller RNAs.
Gene regulation by long non-coding RNAs and its biological ...
2020年12月22日 · Evidence accumulated over the past decade shows that long non-coding RNAs (lncRNAs) are widely expressed and have key roles in gene regulation. Recent studies have begun to unravel how the...
Small and long non-coding RNAs: Past, present, and future
2024年11月14日 · Here, we present our current understanding of the most extensively studied ncRNAs—microRNAs (miRNAs) and long non-coding RNAs (lncRNAs)—that have contributed to the modern regulatory RNA field in eukaryotes.
Long Non-coding RNA - PMC - PubMed Central (PMC)
Rapid development in genome-wide transcriptional analyses has led to the discovery of a large number of non-coding transcripts, also called long non-coding RNA (lncRNA). LncRNAs harbor biological activities including regulation of protein-coding ...
Mechanisms and Functions of Long Non-Coding RNAs at …
Long non-coding (lnc) RNAs are non-coding RNAs longer than 200 nt. lncRNAs primarily interact with mRNA, DNA, protein, and miRNA and consequently regulate gene expression at the epigenetic, transcriptional, post-transcriptional, translational, and post-translational levels in a variety of ways.