Lipid-Based Nanoparticles for Drug/Gene Delivery: An Overview …
2023年8月21日 · In this review, we introduce the main types of LNPs used in drug formulations such as liposomes, nanoemulsions, solid lipid nanoparticles, nanostructured lipid carriers, and lipid polymer hybrid nanoparticles, focusing on their main physicochemical properties and therapeutic potential.
Lipid Nanoparticles for Drug Delivery - Wiley Online Library
2021年11月25日 · Particle size is a critical parameter for nanoparticle drug delivery applications. The average particle size of LNPs is normally between 100 and 400 nm, and LNPs with particle sizes ranging from 10 to about 150 nm are desirable …
Lipid nanoparticles for mRNA delivery - Nature Reviews Materials
2021年8月10日 · Lipid nanoparticles have successfully entered the clinic for the delivery of mRNA; in particular, lipid nanoparticle–mRNA vaccines are now in clinical use against coronavirus disease 2019...
Solid Lipid Nanoparticles for Drug Delivery: Pharmacological …
2020年10月30日 · Pharmaceutical applications of lipid nanocarriers are a burgeoning field for the transport and delivery of a diversity of therapeutic agents, from biotechnological products to small drug molecules.
Lipid Nanoparticles─From Liposomes to mRNA Vaccine Delivery…
2021年6月28日 · Lipid nanoparticles (LNPs) have emerged across the pharmaceutical industry as promising vehicles to deliver a variety of therapeutics. Currently in the spotlight as vital components of the COVID-19 mRNA vaccines, LNPs play a key role in effectively protecting and transporting mRNA to cells.
At the same time, lipid nanoparticles have also demonstrated enormous potential in delivering nucleic acid drugs as evidenced by the approval of two RNA therapies and mRNA COVID-19 vaccines.
Exosomes─Nature’s Lipid Nanoparticles, a Rising Star in Drug Delivery ...
2022年11月10日 · Lipid nanoparticle technologies together with other nanotechnological platforms for drug delivery have improved the efficiency, selectivity, residence time, and biodistribution of traditional drug carrier systems while reducing their drawbacks. However, the clinical application of the lipid nanocarriers has experienced substantial difficulties ...
(PDF) Lipid Nanoparticles for Drug Delivery - ResearchGate
2021年11月25日 · In this review, an overview on different classes of lipid nanoparticles, including liposomes, solid lipid nanoparticles, and nanostructured lipid carriers, is first provided, followed...
Solid Lipid Nanoparticles for Drug Delivery: Pharmacological …
Pharmaceutical applications of lipid nanocarriers are a burgeoning field for the transport and delivery of a diversity of therapeutic agents, from biotechnological products to small drug molecules.
Lipid-based nanoparticles as drug delivery carriers for cancer …
It has been clinically proven that lipid-based nanoparticles, including liposomes, solid lipid nanoparticles (SLNs), and nanostructured lipid carriers (NLCs) are incredibly effective at delivering both hydrophobic and hydrophilic medicines (2, 3).