2024年12月25日 · KLF13 (KLF Transcription Factor 13) is a Protein Coding gene. Diseases associated with KLF13 include Autism Spectrum Disorder and Epilepsy . Among its related …

2024年11月6日 · We identify Klf13 as the primary candidate gene that is associated with genome-wide transcription changes resulting in higher levels of proinflammatory cytokines, enhanced T …

2025年2月8日 · KLF13 is critical for the activation of the HPV productive life cycle and is likely involved in initiation and progression of cervical cancer. Knockdown of either FBW7gamma or …

2020年4月15日 · Our results show that the S156N and P163S variants may affect the transcriptional function of KLF13 and physical interaction with TBX5. These results identified …

2016年4月4日 · Here we show that the transcription factor Kruppel-like factor 13 (KLF13) has a critical role in the HPV life cycle. KLF13 is overexpressed in HPV-positive keratinocytes and …

2020年6月8日 · Our study reveals that KLF13 acts as a tumor suppressor in CRC through negatively regulating HMGCS1-mediated cholesterol biosynthesis.

KLF13 recruits a repressor complex comprising SIN3A and histone deacetylase 1 (HDAC1) to the TGF-β target genes, limiting the profibrotic effects of TGF-β. Temporary upregulation of TGF-β …

2024年8月11日 · In a patient exhibiting attention deficit hyperactivity disorder (ADHD) combined with both neurodevelopmental and psychiatric symptoms, whole-exome sequencing (WES) …

The Krüppel-like factor 13 (KLF13) has emerged as an important transcription factor involved in essential processes of the central nervous system (CNS). It predominantly functions as a …

2023年7月7日 · Results showed that KLF13 directly regulates the expression of several genes involved in the JAK-STAT pathway, including Jak1, Jak2, Jak3, and Socs1, by associating with …