The interleukin 4 (IL4, IL-4) is a cytokine that induces differentiation of naive helper T cells (T h 0 cells) to T h 2 cells. Upon activation by IL-4, T h 2 cells subsequently produce additional IL-4 in …

We recently showed that IL-4, a T-cell-derived cytokine, is a critical participant in higher brain functions such as memory and learning (5). Mice lacking IL-4 demonstrate cognitive …

Interleukin-4 (IL-4) is a four-α-helical bundle type I cytokine with broad pleiotropic actions on multiple lineages. Major actions of IL-4 were initially discovered for B and T cells, but this …

Interleukin (IL)-4 and IL-13 control the phenotype of a variety of cells in health and disease. Their receptor system, signaling cascades, and functional properties have gained clarity in the past …

Review on three IL-4-related branch points for immune regulation: alternative splicing of IL-4, differential receptor engagement, and differential regulation of macrophage activation by IL-4.

2005年7月19日 · Interleukin-4 (IL-4) is a cytokine produced by T (H)2 type helper T cells and by mast cells, basophils, and eosinophils. This cytokine can elicit many responses, some of which …

2012年11月1日 · In this article, we focus on the basic immunology of IL-4 as it pertains to the CNS, and in particular to the question of how and where it operates to influence cognition. We …

Interleukin-4 is a multifunctional cytokine that plays a critical role in the regulation of immune responses. Its effects depend upon binding to and signaling through a receptor complex …

Interleukin 4 (IL-4) is a pleiotropic type I cytokine that controls both growth and differentiation among haemopoietic and non-haemopoietic cells. Its receptor is a heterodimer.

2005年7月19日 · Interleukin-4 (IL-4) is a cytokine produced by T H 2 type helper T cells and by mast cells, basophils, and eosinophils. This cytokine can elicit many responses, some of which …