Interleukin 13 (IL-13) is a cytokine that is responsible for promoting Th2 responses in humans and is released by T cells, mast cells, and eosinophils. It is typically associated with allergic …

IL-13 is a cytokine that is produced by different T-cell subsets and dendritic cells. IL-13 shares many biologic activities with IL-4. This is due to the fact that IL-13– and IL-4–receptor …

IL-13 was first recognized for its effects on B cells and monocytes, where it upregulated class II expression, promoted IgE class switching and inhibited inflammatory cytokine production. It …

IL-13 down-regulates PGE2 both directly and indirectly through effects on PGES and COX-2. IL-13 also induces 15-LO that is correlated with asthma severity. IL-13 induction of 15-LO …

This review provides an update on the role of IL-13 in AD and discusses the different strategies aimed at interfering with its biologic activity as well as their potential in a precision medicine …

2. What We Know about IL-13 Comes from Studies of Its Biology in the Immune System. The cytokines Interleukin 13 (IL-13) and interleukin-4 (IL-4) are two secreted proteins recognized …

Interleukin 13 (IL-13) is an immunoregulatory cytokine predominantly secreted by activated Th2 cells. IL-13 appears to be necessary in the effector phase of inflammation and has been …

2025年2月8日 · IL-13 can act on macrophages both before and after HIV-1 infection to interfere with virus replication by blocking the completion of reverse transcription, decreasing virus …

2015年4月2日 · Interleukin-13 (IL-13) as a pleiotropic cytokine acts through the IL-13Ra1/IL-4Ra complex to induce activation responses which contribute to the inflammatory diseases. …

IL-13 is a critical mediator of allergic inflammation. Although it shares many functional properties with IL-4, it has been shown to have distinct functions. Furthermore, IL-13 is more important …