Insulin-like growth factor 1 receptor - Wikipedia
IGF-1 binds to at least two cell surface receptors: the IGF1 Receptor (IGFR), and the insulin receptor. The IGF-1 receptor seems to be the "physiologic" receptor—it binds IGF-1 at …
胰岛素(Insulin)及其受体家族 - 知乎 - 知乎专栏
胰岛素样生长因子受体 ( insulin-like growth factor receptor，IGFR) 胰岛素受体相关受体 ( insulin receptor-relatedreceptor，IRR) 胰岛素受体家族成员在与各自的配体（如胰岛素(insulin)、胰岛 …
胰岛素样生长因子 - 百度百科
胰岛素样生长因子受体igf必须与载体蛋白igf结合蛋白（igfbp）解离后与其特有受体结合才能发挥生物效应。igf受体分两型，即igf-Ⅰ受体（igf-Ⅰr）和igf-Ⅱ受体（igf-Ⅱr），前者属酪氨酸激酶 …
Structural basis of the activation of type 1 insulin-like ... - Nature
2019年10月8日 · The type 1 insulin-like growth factor receptor (IGF1R) is a class II receptor tyrosine kinase (RTK), belonging to the insulin receptor family, that plays critical roles in cell …
胰岛素受体亚型和胰岛素生长因子样受体：对细胞信号传导、癌发 …
这篇全面的综述全面探讨了胰岛素受体 (ir) 亚型和胰岛素样生长因子受体 (igfr) 在胰岛素和胰岛素样生长因子 (igf) 信号传导 (iis) 途径中的复杂参与。 这个复杂的系统包含配体、受体和结合蛋 …
什么是胰岛素样生长因子1受体(IGF-1R)？ - 知乎
胰岛素样生长因子1受体 (igf-1r)位于人类细胞表面，是受激素胰岛素样生长因子1 (igf-1)和另一相关激素胰岛素样生长因子2 (igf-2)激活的跨膜受体，属于酪氨酸激酶受体的一大类。. igf-1r介 …
Insulin receptor (IR) and insulin-like growth factor receptor 1 (IGF …
Insulin and insulin-like growth factor (IGF) signaling system, commonly known for fine-tuning numerous biological processes, has lately made its mark as a much sought-after therapeutic …
IGF1R insulin like growth factor 1 receptor [ (human)]
High coexpression of both insulin-like growth factor receptor-1 (IGFR-1) and epidermal growth factor receptor (EGFR) is associated with shorter disease-free survival in resected non-small …
Nat Commun：揭示胰岛素样生长因子受体IGF1R激活的分子机制
2019年10月13日 · 一型胰岛素样生长因子受体（Type 1 insulin-like growth factor receptor， IGF1R）属于受体酪氨酸激酶家族（receptor tyrosine kinases， RTKs），胰岛素受体亚家 …
Definition of IGFR - NCI Dictionary of Cancer Terms
A protein found on the surface of some types of cells that binds to insulin-like growth factor (IGF). This causes the cells to grow and divide. IGFR is found at high levels on the surface of several …